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A woman lifts a weighted bar above her head.

Signal Molecule Variants Explain Why Some People Lose Weight Slower After Exercise

Researchers have identified a signal molecule variant that helps explain why some people lose weight more slowly after exercise.
3D yellow oblong bacteria particles on a blue background.

Respiratory Bacteria Survive by Switching Off the Immune System

Researchers have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.
A laboratory scientist handling test tubes containing blood samples

Type 1 Diabetes Leaves Distinct T-Cell Signatures in the Blood

A study has found distinct signatures in T cells in blood samples from children with newly diagnosed type 1 diabetes. These T-cell signatures could be used to develop better biomarkers for evaluating type 1 diabetes risk.
A virus-specific T cell in the vascular system of a liver with chronic hepatitis B virus infection.

Liver Cells Put a “Sleep Timer” On Immune Cells in Chronic Hepatitis B Infection

A team has discovered that cells in blood vessels in the liver start a “sleep timer” that switches off immune cells, and targeting this mechanism could be a starting point for immunotherapies.
Pink cells.

Long-Lived Proteins Are Essential to Egg Cell Maintenance

Long-lived proteins in egg cells appear to help maintain fertility for as long as possible.
Hands in pink vinyl gloves hold a test tube containing blood.

Platelets and Monocytes Communicate in Newly Discovered Immune Pathway

According to research platelets communicate with monocytes and increase their inflammatory capacity. By understanding the platelet-monocyte interaction, the team hope to improve the treatment of immune disorders and associated diseases.
A white mouse held in a gloved hand.

Researchers Create First Mouse Model With a Functioning Human Immune System

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.
A stem cell dividing in two with other cells and DNA helices in the background

Unmasking the True Identity of Gut Stem Cells

Columbia researchers have found that Lgr5+ cells descend from the gut’s true stem cells. This case of mistaken identity may explain why regenerative medicine has not lived up to its promise.
A person with an IV in their hand.

Tissue Stiffness Can Impact Pancreatic Cancer Resistance to Chemotherapy

Researchers have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
Three DNA helices

Scientists Capture a Key Step in Gene Transcription for the First Time

A new study has described E. coli RNAP in the act of opening the transcription bubble. The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription.