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Researchers Create Renewable Source of Cancer-fighting T Cells
Researchers Create Renewable Source of Cancer-fighting T Cells
News   Jan 18, 2019

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells — which can give rise to every cell type in the body and which can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells.

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World’s First Genetically Enhanced Human Vascular Cells
World’s First Genetically Enhanced Human Vascular Cells
News   Jan 18, 2019

Scientists have generated the world's first genetically enhanced human vascular cells by targeting a single longevity gene, FOXO3.

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Another Piece of Ebola Virus Puzzle
Another Piece of Ebola Virus Puzzle
News   Jan 18, 2019

Researchers have discovered the interaction between an Ebola virus protein and a protein in human cells that may be an important key to unlocking the pathway of replication of the killer disease in human hosts.

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New Material Could Drive Wound Healing
New Material Could Drive Wound Healing
News   Jan 18, 2019

Imperial researchers have developed a new bioinspired material that interacts with surrounding tissues to promote healing.

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Interference with Estrogen Signaling Sends Bone Formation into Overdrive
Interference with Estrogen Signaling Sends Bone Formation into Overdrive
News   Jan 18, 2019

Deleting a certain type of estrogen receptor in an area of the hypothalamus dramatically increased bone density and strength in female mice, opening up many therapeutic possibilities for improving women's health.

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Human Blood Vessels Organoids a Model for Diabetes Research
Human Blood Vessels Organoids a Model for Diabetes Research
News   Jan 17, 2019

This model will advance research in vascular diseases like diabetes, identifying a key pathway to potentially prevent changes to blood vessels—a major cause of death and morbidity among those with diabetes.

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Blindness Prevented in Animal Models of Retinal Degeneration
Blindness Prevented in Animal Models of Retinal Degeneration
News   Jan 17, 2019

Using a novel patient-specific stem cell-based therapy, blindness was prevented in animal models of geographic atrophy, the advanced 'dry' form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older.

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Halting Inflammation at the Flick of a Switch
Halting Inflammation at the Flick of a Switch
News   Jan 16, 2019

A novel regulator of the immune system has been identified that deactivates the innate immune system and could prevent certain diseases caused by an excessive activation of the immune system.

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Altering Stathmin2 Expression Rescues Motor Neuron Growth
Altering Stathmin2 Expression Rescues Motor Neuron Growth
News   Jan 16, 2019

Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis (ALS), a neurological disease that is difficult to diagnose and treat.

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Hindering Melanoma Metastasis with FDA-approved Drug
Hindering Melanoma Metastasis with FDA-approved Drug
News   Jan 16, 2019

An FDA-approved drug has been identified that, when used with surgery, hampers metastasis in an animal model. Originally developed and approved ~65 years ago to control blood pressure, the medication resperine also prevents what are known as tumor-derived extracellular vesicles from fusing to healthy cells and sharing their cargo of disease-promoting molecules.

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