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Course-correcting Stem Cells that Missed the Memo

News   Nov 20, 2018 | Original story from Washington University School of Medicine in St Louis

10-20% of Cells in a Kidney Organoid Found to be Non-Renal

Scientists at Washington University School of Medicine in St. Louis have identified rogue cells – namely brain and muscle cells – lurking in kidney organoids, an indication that the “recipes” used to coax stem cells into becoming kidney cells inadvertently are churning out other cell types. The researchers also demonstrated they could prevent most of those wayward cells from forming, an approach that could be adopted by scientists working with other organoids, such as those of the brain, lung or heart. The image shows brain neurons in red and kidney cells in green. Image credit: Washington University School of Medicine in St Louis.



From Ion Channels to Whole Brain Stimulation


Pores at the surface of neurons and muscle cells control your every thought, movement; the very beating of your heart. The way the pores behave shapes signals in the form of ions moving across the cell surface. For the first time, researchers have mapped the behavior of the largest family of these voltage-gated ion channels: Kv channels.


Kids Need More Sleep, Less Screen, Says HALO Group


A paper published today in Pediatrics suggests that children and youth who do not sleep enough and use screens more than recommended are more likely to act impulsively and make poorer decisions.


Watching the Brain's "Firework Memories"


A new paper a neuronal mechanism central to human free recall that sees orchestrated burst of synchronous activation by about 15% of hippocampal neurons.



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