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Cones Affected by Retinal Degeneration May Not Actually Be Dormant
New murine research suggests that “dormant” cone photoreceptors in the degenerating retina continue to function, producing responses to light and driving retinal activity for vision.
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Myeloid Cells Can Harbor HIV for Years Even With Therapy
HIV can persist in a subset of white blood cells even if the patient is taking antiretroviral therapy, reports a new study.
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Protein Family Is Key for Powerful Muscle Fiber Generation
A protein family’s role in the regulation of fast-twitch muscle fibers – those involved in fast and powerful movements – has been identified by scientists at the University of Tsukuba. The research is published in Cell Reports.
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How Cancer Gene Tricks Immune Cells To Stand Down
The sugars present on the surface of cancer cells are crucial to oncogene-mediated immune evasion, according to a new study.
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Key Elements of Super-Efficient Energy Transfer in Photosynthesis Studied
LMU chemists use high-precision quantum chemistry to study key elements of super-efficient energy transfer in an important element of photosynthesis.
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Somatic Mutations Can Impact Differentiation of iPSC Lines
Induced pluripotent stem cells offer therapeutic potential and are a valuable tool for understanding how diseases develop. New research shows that such stem cell lines should be screened for genetic mutations to ensure the accuracy of the disease models.
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Cell Population That Causes Graft Versus Host Disease Identified
Researchers at the Carbone Cancer Center have identified the cells that can cause graft versus host disease, the most common complication of bone marrow transplants.
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A Meta-Scale Approach to Quantifying the Human Proteome
A new study released today in the journal Nature Biotechnology outlines a meta-scale approach to quantifying the human proteome and the massive number of protein variants produced by the human body.
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New Drug Keeps Mice Slim Even on a Sugary, Fatty Diet
Researchers have developed a small-molecule drug that prevents weight gain and adverse liver changes in mice fed a high-sugar, high-fat Western diet throughout life.
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Age-Induced Changes to Sperm Contribute to Offspring's Disease Risk
Researchers performed reduced representation bisulfite sequencing (RRBS) on 73 sperm samples of males attending a fertility center in Germany. Collectively, their data support the conclusion that age-induced methylation changes in the sperm epigenome contribute to the increased offspring disease susceptibility for neurodevelopmental disorders.
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