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Cones Affected by Retinal Degeneration May Not Actually Be Dormant

New murine research suggests that “dormant” cone photoreceptors in the degenerating retina continue to function, producing responses to light and driving retinal activity for vision.
A human cell, colorized in blue, being infected by yellow HIV particles.
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Myeloid Cells Can Harbor HIV for Years Even With Therapy

HIV can persist in a subset of white blood cells even if the patient is taking antiretroviral therapy, reports a new study.
A picture of a person lifting weights at the gym.
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Protein Family Is Key for Powerful Muscle Fiber Generation

A protein family’s role in the regulation of fast-twitch muscle fibers – those involved in fast and powerful movements – has been identified by scientists at the University of Tsukuba. The research is published in Cell Reports.
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How Cancer Gene Tricks Immune Cells To Stand Down

The sugars present on the surface of cancer cells are crucial to oncogene-mediated immune evasion, according to a new study.
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Key Elements of Super-Efficient Energy Transfer in Photosynthesis Studied

LMU chemists use high-precision quantum chemistry to study key elements of super-efficient energy transfer in an important element of photosynthesis.
Representation of human stem cells.
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Somatic Mutations Can Impact Differentiation of iPSC Lines

Induced pluripotent stem cells offer therapeutic potential and are a valuable tool for understanding how diseases develop. New research shows that such stem cell lines should be screened for genetic mutations to ensure the accuracy of the disease models.
Representation of human cells.
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Cell Population That Causes Graft Versus Host Disease Identified

Researchers at the Carbone Cancer Center have identified the cells that can cause graft versus host disease, the most common complication of bone marrow transplants.
A Meta-Scale Approach to Quantifying the Human Proteome content piece image
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A Meta-Scale Approach to Quantifying the Human Proteome

A new study released today in the journal Nature Biotechnology outlines a meta-scale approach to quantifying the human proteome and the massive number of protein variants produced by the human body.
One white pill on a yellow background.
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New Drug Keeps Mice Slim Even on a Sugary, Fatty Diet

Researchers have developed a small-molecule drug that prevents weight gain and adverse liver changes in mice fed a high-sugar, high-fat Western diet throughout life.
A picture of sperm.
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Age-Induced Changes to Sperm Contribute to Offspring's Disease Risk

Researchers performed reduced representation bisulfite sequencing (RRBS) on 73 sperm samples of males attending a fertility center in Germany. Collectively, their data support the conclusion that age-induced methylation changes in the sperm epigenome contribute to the increased offspring disease susceptibility for neurodevelopmental disorders.
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