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Harnessing Bird Retrotransposon To Improve Gene Therapy
A new approach uses a retrotransposon from birds to insert genes into "safe harbors" in the genome, holding promise for gene therapy.
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Age-Related Cell Changes Promote Pancreatic Cancer Growth
Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research.
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“Testes in a Dish” Advance Male Fertility Research
The artificial testicles will contribute to the advancement of research in male fertility and sexual development disorders, and are expected to facilitate the eventual production of sperm in the laboratory.
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Molecule That Reactivates Dormant Cancer Cells Discovered
A molecule that can reactivate dormant breast cancer cells and nudge them toward metastasis has been identified. The researchers also showed that inhibiting this molecule can reduce metastases.
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Understanding Liver Generation
Researchers at Peter Mac have made a key discovery in liver regeneration that may have important implications for liver cancer. The joint research has identified how the liver is triggered to regrow when damaged.
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New Toolbox Enables Genome Engineering Without CRISPR
Belgian researchers have developed a new toolbox of 16 different short DNA sequences that allow triggering controlled and specific recombination events in any genome.
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Targeting “Undruggable” Proteins Opens New Doors for Neurodegenerative Disease Treatment
Researchers unveil groundbreaking research with the potential to alter the treatment landscape for neurodegenerative diseases (NDs). The study introduces a pioneering approach aimed at combating conditions such as Alzheimer’s disease.
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Ancient Retroviruses Supported the Evolution of Vertebrate Brains
A retrovirus-derived genetic element is to thank for myelin production – and by extension, large brains – in vertebrates.
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Telomerase Can Run Amok, Adding Telomeres to Damaged DNA
The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts.
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Triggering Asexual Propagation of Crop Plants
When the female gametes in plants become fertilized, a signal from the sperm activates cell division, leading to the formation of new plant seeds. This activation can also be deliberately triggered without fertilization.
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