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Ancient DNA Tells the Origin Story of Ashkenazi Jews

DNA extracted from remains of a 14th-century Jewish cemetery has provided insights into the origins of the Ashkenazi Jewish population.
Dynein intermediate chain structure showing folded WD repeat domain and disordered N-terminal domain.
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New Analysis of Cellular "Vehicles" Drives a Deeper Understanding of Neurodegenerative Diseases

Oregon State University scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor protein whose malfunction is associated with many disorders.
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Why Do Some Vaccines Create Long-Lived Responses? Ask the Researcher

In this Ask the Researcher, we spoke with Professor David Tarlinton to learn more about long-lived plasma cells; how they are made and how they are stored.
Cartoon of a doctor holding a measuring tape around an overweight individual's waist.
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How Enlarged Fat Cells Can Cause Metabolic Disorders

If you gain weight, the fat cells in the body get bigger. So in the extremely obese, those fat cells are greatly enlarged. Researchers have now shown how enlarged fat cells can cause metabolic diseases.
A DNA double helix.
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Mystery About the Origins of Introns Solved

A new study from UC Santa Cruz has pointed toward a proposed mechanism for the formation of introns in the genomes of prokaryotes.
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Protein Spheres Protect Sensitive Parts of the Cancer Genome

Hollow spheres made of MYC proteins open new doors in cancer research.
Representation of a human brain.
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Novel Method Automates the Growth of Cerebral Organoids

The new system can increase reproducibility in cerebral organoid research and shows promise for lowering levels of cellular stress.
Two cancer cells dividing.
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Cell Division Enzyme Identified as Possible Cancer Treatment Target

Researchers studying how cancer cells divide have revealed potential new viable therapeutic targets for cancer treatment.
Graph showing CD8 T cell populations in healthy vs individuals with genetic variants and autoimmune diseases.
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Rogue Immune Cells Linked to Leukaemia Are a Key Driver of Autoimmune Diseases

Scientists have pinpointed rogue immune cells as a major contributor to autoimmune conditions like rheumatoid arthritis and aplastic anaemia.
An amami spiny rat standing on leaves and twigs.
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New Sex-Determination System Revealed in Rats

Researchers have uncovered the genetic basis for sexual differentiation in the Amami spiny rat, one of the species the lacks a Y chromosome and the Sry gene.
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