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Missing Step in Lipid Formation Could Enable Detection of Past Climate
The missing step in the formation of a lipid molecule that allows certain single-celled organisms to survive the most extreme environments on Earth has now been deciphered.
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How Mitochondrial Dysfunction Leads to Premature Aging
Researchers at the University at Buffalo and their collaborators have developed powerful new ways to study and potentially reverse the cellular mechanisms that cause mitochondrial diseases and premature aging.
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Diseased Connective Tissue Cells Reorder Their DNA Incorrectly
With super-resolution imaging, Penn Medicine researchers discovered that cells change the physical structure of their genome when they’re affected by disease.
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Human Skin Cells Reprogrammed Into Aged Neurons To Study Neurodegenerative Disorders
Researchers have developed a new method for studying age-related brain disorders.
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Improved Methods for Micro-Organosphere Generation Developed
Scientists devise novel methods in their microfluidic technology to produce optimized platforms for tissue and disease modeling.
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Repurposed Diabetes Drug May Be Key To Treating Muscle Wasting Disease
A new study has reported that a novel member from a class of anti-diabetes drug could be used to treat a muscle wasting disease by suppressing inflammation.
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GlyNAC Improves Many Age-Associated Defects in Older Humans
A clinical trial has revealed that supplementation with GlyNAC – a combination of glycine and N-acetylcysteine – improves a range of symptoms associated with aging, including inflammation and insulin resistance.
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Immune Cell Model Paves the Way to Helping Immunocompromised Children
Researchers have successfully engineered human immune cells to model an infection common among immunocompromised children in a breakthrough discovery, paving the way for new drug testing and treatments.
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New Method for RNA-Sequencing in Single Cells – Without Killing the Cell
Researchers present a novel approach to single-cell RNA sequencing (scRNA-seq) called “Live-seq”, which enables the extraction of mRNA from single cells without killing the cell. The method is published in Nature.
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New Technology Profiles RNA Structure at the Resolution of a Single Molecule in Live Cells
Newly developed technology has revealed the impact of environmental conditions on the dynamic structures of RNAs in living cells.
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