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A Blueprint for Turning Stem Cells Into Sensory Interneurons
A study has mapped out how sensory interneurons form from stem cells, a key step in developing cell therapy to restore sensation in people with spinal cord injuries.
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Scientists Create New Non-Opioid Painkiller With Fewer Side Effects
Researchers have developed a promising new non-opioid painkiller, potentially with fewer side effects compared to other potent painkillers, and a unique mode of action, potentially opening a new pipeline for the development of analgesic drugs.
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Pancreas Organoids Grown From Patients Predict Chemotherapy Response
Patient-derived organoids could help direct pancreatic cancer treatment strategy, as they can predict how the tumor will respond to chemotherapy before surgery.
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A New Tool for More Personalized Cell Therapies
A University of Minnesota Twin Cities team has, for the first time, developed a new tool to predict and customize the rate of a specific kind of DNA editing called “site-specific recombination.” The research paves the way for more personalized, efficient genetic and cell therapies for diseases such as diabetes and cancer.
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Egg Cells Maintain Reproductive Longevity by Switching to "Standby Mode"
Researchers have discovered a mechanism that may explain how immature human egg cells are able to survive for long periods of time without losing their reproductive capacity, by modifying their metabolism and switching to a cellular "standby mode".
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Human Brain Cells Grown in Mice Could Lead to Alzheimer's Therapy
A novel study involving human brain cells grown in mice provides insight that could lead to potential therapy for Alzheimer’s disease.
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60 Million Years of Penguin Evolution Revealed
A study has revealed that penguin evolution was driven by changes in climate and ocean currents.
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Unpicking the Complex Genetics Behind Alcohol, Cigarette and Substance Addiction
Researchers from the University of North Carolina are working to understand the genetic differences that underpin a person's proclivity to substance abuse and have identified genes linked to cigarette smoking and alcohol.
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Common Cancer Gene Regulates RNA “Dark Matter”
A new study has shown that a key genetic mutation that occurs early on in cancer alters RNA “dark matter” and causes the release of previously unknown RNA biomarkers.
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Overly Restricting Salt Intake May Be Counterproductive for Heart Failure Patients
Restricting salt intake is considered a key component of heart failure treatment, but restricting it too much may actually worsen the outcomes for people with a common form of the condition, suggests research.
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