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“Jumping” Protein Helps To Keep Cells Healthy

There is a lot of potential for RNAi therapeutics, and Cold Spring Harbor Laboratory (CSHL) researchers are working hard to paint a complete picture of the process, to improve therapies today and make better ones tomorrow.
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Endothelial Cell Signaling May Drive Liver Cancer Progression

Researchers use lab-grown mini liver tumors co-cultured with endothelial cells, revealing chemokine signaling by these cells that drive liver cancer progression and poor survival in patients.

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Increasing Cervical Screening Interval to Five Years Is Safe With Negative HPV Test

A study of 1.3 million women has indicated that increasing the cervical screening interval from three to five years is safe for people aged 24–49, following a negative HPV test.
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New Imaging Approach Provides Detailed Images of Organoids

Researchers have developed a new imaging system to quickly produce high-resolution 3D images in real-time, providing a quantitative analysis of organoids.
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Gene Regulation a Key Piece in the Lifespan Puzzle

Researchers have identified thousands of genes associated with lifespan and have found two key regulatory mechanisms that regulate their expression.
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How HIIT Can Reshape Metabolism

Scientists have shed new light on the effects that high-intensity interval training (HIIT) has on human skeletal muscle, according to a study in men published today in eLife.
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Cellular Process Could Reveal Insights Into Aging-Related Diseases

A team of researchers has identified the molecular and cellular mechanisms that regulate selective autophagy in the fruit fly Drosophila melanogaster.
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Understanding Ketamine’s Action on Potassium Channels Could Help To Improve Treatment of Depression

Researchers have revealed new details about how ketamine' mechanism of action on potassium channels in neurons, which could help to develop new treatments for depression.
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Breast Cancer and Diabetes Join Forces To Promote Disease

Breast cancer and diabetes are both common diseases, with past epidemiological data suggesting the two are linked. A new study has identified a mechanism by which breast cancer cells could impair the function of pancreatic islet cells.
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Amyloid-Beta Misfolding and Clumping Causes Cells To Overheat and “Fry”

Researchers from the University of Cambridge have identified that as amyloid-beta misfolds and clumps together, it releases heat that "fries" the cell and potentially induces more and more aggregates to form.
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