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Examination of Endangered Species’ Stem Cells Unveils Ancient Genetic Links Between Mammals
Researchers have produced iPS cells from the endangered Grévy’s zebra using human reprogramming factors, and found that those factors are evolutionarily conserved among animal species.
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Microbiome Mediates Slowed Immune Aging Linked to a Calorie-Restricted Diet
Researchers have shown that the positive effect of a calorie-reduced diet on the immune system is mediated by an altered gut microbiome, which slows down the deterioration of the immune system in old age.
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SARS-CoV-2 Can Directly Infect Human Kidney Cells
According to research, SARS-CoV-2 can directly infect a specialized type of kidney cell and hijack the cell’s machinery to replicate, causing injury and COVID-19-associated kidney disease.
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New Cardiac Tissue Model Created
A combination of tissue engineering and nanotechnology has enabled researchers to build a miniature replica of a heart chamber that beats by itself.
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Exploring the Evolution of Protein Translation
A new study has shed light on how tRNA-like components act as scaffolds for peptide bond formation between amino acid-bound "RNA minihelices," which are half tRNA-like molecules.
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This Protein Stops the Pancreas From Digesting Itself
Salk scientists report in the journal Gastroenterology that a protein known as estrogen-related receptor gamma (ERR ɣ) is critical for preventing pancreatic auto-digestion in mice.
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Genetic Component of Cancer Is Just One Piece of the Puzzle
A recent review has highlighted the roles of the metabolome and the eposome in cancer development, encouraging researchers to view cancer through a multiomics lens.
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Whole-Genome Analysis of 12,000 Patients Reveals “Treasure Trove” of Cancer Insights
Scientists and clinicians from the University of Cambridge – supported by Cancer Research UK (CRUK) – have conducted the largest whole-genome sequencing analysis of cancer tumors to date.
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Lab-Grown, Self-Sustainable Muscle Cells Repair Muscle Injury in Mice
Induced pluripotent stem cells have been used to make muscle stem cells that have been shown to repair muscle injury in mice.
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Cellular Diversity of Esophageal Tissue Revealed
Researchers have defined 11 subsets of cells found in the esophagus of mice, information that could potentially help clinicians diagnose or treat certain types of cancer.
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