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Structural Bio Paired With Computational Design To Create Anticancer Agent
Researchers have used computational design to combine the structures of three molecular fragments into a single chemical compound that was able to dock in a binding pocket on tubulin and disable it. This caused disruption to the cytoskeletal structure of cancer cells, leading to cell death.
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Novel Tissue Engineering Strategy Developed
A novel, laser-based 3D printing technique has been used to create a scaffold for tissue engineering and has been shown to successfully produce cartilage and bone tissue from stem cells.
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New Cell Type Discovered in Salivary Glands
Scientists have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.
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Old Skin Cells Can Be Reprogrammed To Regain Their Youth
Scientists have created a new method that enables stem cells to be converted back to their original, specialized form, but "rejuvenated".
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Innovative Lens Provides New Route to Atomic Resolution Electron Microscopy
Researchers have proposed a new method to form an electron lens that uses a light field instead of the electrostatic and magnetic fields employed in conventional electron lenses.
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Study Reveals How Mitochondria Report Stress
The mechanism by which mitochondria recognize and report stress has been revealed, offering a possible new approach for treating neurodegenerative diseases.
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Study Reveals How To Rejuvenate the Immune System of Elderly People
A new study identifies a reason why older adults are significantly more susceptible to infectious diseases than younger people, paving the way for new potential therapeutic targets to rejuvenate the immune system.
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Virally-Programmed Extracellular Vesicles Designed To Shrink Tumors
A research team has designed a virus that selectively infects cancer cells and causes the infected cells to release RNA-containing extracellular vesicles that blunt the antiviral response of surrounding cancer cells.
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Receptor That Controls Appetite and Body Weight Identified
Progress in the development of a drug to treat metabolic syndrome has been furthered by identifying a receptor that controls appetite and body weight.
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Human Lung Chip Helps To Identify Potential Treatments for Respiratory Diseases
Research has revealed that the constant pattern of stretching and relaxing caused by breathing generates immune responses against invading viruses.
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