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Novel SERS-Based Method Could Provide Easy and Early Diagnosis for Hepatic Inflammation
Scientists have developed a novel biosensor based on aptamer-combined surface-enhanced Raman spectroscopy (SERS) to detect inflammatory microRNA-122 (miR-122) in cell-secreted exosomes.
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How Cells Feel Curvature
Curved surfaces are found everywhere in biological tissues and evidence suggests that cells are able to sense whether they are in flat or curved environments. A study has now uncovered the mechanisms that regulate the cells’ behavior depending on the change of the environment’s curvature.
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How Do Moles Turn Into Melanoma?
Moles and melanomas are both skin tumors that come from the same cell called melanocytes. The difference is that moles are usually harmless, while melanomas are cancerous and often deadly without treatment. A researcher has explained how these skin tumors form and why moles can change into melanoma.
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Cryo-EM Enables Team To Study How DNA Replication Machinery Assembles
Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
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Deep Learning Shines Light on Protein Interactions
Scientists are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.
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Identification of Microplastics in the Human Body Assisted by Deep Learning
Using dark-field microscopy and deep learning, scientists studied microplastics in living cells to help understand what detrimental effects they may be having.
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Rheumatoid Arthritis Discovery Could Improve Treatments
Researchers have linked the T-cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency. The information could help to develop effective treatments.
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Tracking Circadian Rhythms in Cancer Cells
Prof. Michelle Farkas from the University of Massachusetts Amherst has been awarded a grant by the National Institutes of Health to develop next-generation tools to track and manipulate circadian rhythms in cancer cells.
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Deleting Dysfunctional Cells Alleviates Diabetes
Researchers say that eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes. This discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.
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Functional Bile Duct Cells Generated From Stem Cells
Researchers have discovered a way to generate functional cells from stem cells that could open new treatment avenues for people with cystic fibrosis who have liver disease.
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