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Plans and Goals for the Human Proteoform Project
Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body.
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Vitamin D Metabolite Involved in Shutting Down Inflammation
Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19.
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Puppyhood Diet May Impact a Dog's Allergies Later in Life
Researchers have studied the relationship between allergy and atopy-related skin symptoms at adult age and different types of diets as well as individual dietary food items in the same dogs when they were puppies.
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New Clues About the Process of Meiosis
Understanding how mutations arise in germ cells is important because they can cause miscarriages and genetic diseases. Researchers have used a strain of mutant mice as a means to uncover new clues about the process of meiosis, which forms eggs and sperm.
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Nanoscale "Computer" Activates Protein and Influences Cell Behavior
Researchers have created a computational operation and embedded it into a protein. In doing so, they are now able to rapidly activate the protein using light and the drug rapamycin. When activated, the cells underwent internal changes that enhanced their adhesive capabilities, which ultimately decreased their motility.
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3D Platform Developed To Study Deadly Lung Disease
Researchers have developed a 3D cell culturing platform that allows the study of lung fibroblasts and their microenvironment. The platform enables measurement of cell behaviors and changes involved in the progression of idiopathic pulmonary fibrosis.
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Studying the Life History of Prostate Cancer
Researchers have developed a new way to study the life history of prostate cancer in mice. The method allows scientists to study the behavior and properties of prostate cancer in a setting that accurately mimics the disease in real life.
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Towards an “Off-the-Shelf” Immunotherapy for Cancer
Researchers are one step closer to an “off-the-shelf” cancer immunotherapy that uses rare but powerful immune cells.
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How Cellular Structures Regulate Insulin Secretion "Hotspots"
Scientists have shed new light on how insulin is released from beta cells in the pancreas, with potential implications for understanding more about what happens in diseases such as diabetes.
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Researchers Produce a Single-Cell Chromatin Atlas for the Human Genome
Researchers have produced a single-cell chromatin atlas for the human genome. Precisely delineating accessible chromatin regions in cells of different human tissue types would be a major step toward understanding the role of non-coding DNA in human health and disease.
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