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New Source of Liver Stem Cells Discovered
Researchers from Sanford Burnham Prebys have discovered a new source of stem cells just outside the liver that could help treat people living with Alagille syndrome, a rare, incurable genetic disorder in which the bile ducts of the liver are absent, leading to severe liver damage and death.
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Using CRISPR-Cas9 To Explore Epigenetic Editing in Different Tumor Settings
An increasing number of studies report that proteins do not work in isolation but are part of a complex network of biomolecules, that may differ at various settings or stages of tumor progression.
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Kidney Transplant Patients Vulnerable to Infection by "Innocuous" Bacterium
A study shows that for most people, nocardia, a pervasive bacterium, doesn't cause disease, but those with compromised immune responses are more vulnerable.
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Chemical Probe Aids Understanding of Immune Response
Chemists have created a new sensor to detect chemical changes in immune cells during the breakdown of pathogens. The work could potentially contribute to the early diagnosis and treatment of infectious diseases, such as tuberculosis, that evade certain elements of the body's immune response.
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New Approach Enables Ultra-Sensitive Exosome Biosensing
Circulating tumor exosomes are composed of molecules that reflect the parental cells. But, because they are tiny and complex, the precise detection of exosome-carried biomarkers with molecular specificity has so far been difficult.
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Humans and Chimpanzees Use a Part of Their DNA in Different Ways
Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a difference which, despite all our similarities, may explain why our brains work differently.
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Drug Target for Parkinson’s Disease May Not Be Relevant for All Patients
A new study conducted using mice suggests that targeting the alpha-synuclein protein may not be sufficient to treat the disease and alleviate symptoms in most patients.
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New Insights Into the Cellular Basis of Cystic Fibrosis
Researchers are hopeful that new understanding of cellular defects related to cystic fibrosis could help pave the way for treatment of the disease.
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Stem Cell Population Identified That Is Key for Bone Regeneration
Researchers have identified a subpopulation of MSCs that promote the healing of bone fractures and show an enhanced ability to differentiate into various cell types.
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APOE4 Linked With Better Visual Working Memory in Older Adults
A well-known gene that increases Alzheimer’s risk, called APOE4, has been linked with better visual working memory in older adults.
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