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New Insights on the Genetic Regulation of Blood Cells
Researchers have analyzed a dataset that included more than 31,000 study participants in order to gain significant new insight into the genetic regulation of blood cells.
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Sensor Can Differentiate Which Viruses Are Infectious
Researchers have developed a new sensor that can detect the presence and infectivity of a virus in minutes.
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A Novel Therapeutic Strategy for Ovarian Cancer Subtype With Poor Prognosis
More than 50% of patients with ovarian clear cell carcinomas display mutations in the ARID1A gene. Scientists have found that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway.
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Towards a Unified Theory for DNA Folding
Researchers have used statistical mechanics to explore the phenomenon of so-called expression waves of gene regulation.
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Targeting SARS-CoV-2 Viral Proteases To Prevent Infection
Researchers have shown how SARS-CoV-2 viral proteases attack the host cell, and how existing drugs can be used to stop virus replication in cell culture.
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New Mechanism Underlying Red Blood Cell Aging Revealed
Researchers developed an in vitro assay to investigate hypoxic effects on the metastatic potential and relevant drug resistance of cancer cells.
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Diet Rich in Dairy Fat May Actually Lower Heart Disease Risk
New research amongst the world’s biggest consumers of dairy foods has shown that those with higher intakes of dairy fat - measured by levels of fatty acids in the blood - had a lower risk of cardiovascular disease compared to those with low intakes. The types rather than amount of dairy fat may be what counts.
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Embryo-Like Structures Created From Human Stem Cells
Caltech researchers have created embryo-like structures out of human stem cells. In contrast to natural embryos that are formed by a combination of sperm and egg, these structures are formed by combining so-called pluripotent stem cells, which have the ability to develop into specialized types of cells.
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How Pruning the Cytoskeleton Moves the Cell
Researchers have revealed how stopping the growth of older actin filaments promotes the formation of new ones, thereby maintaining the structure and function of the cytoskeleton, much like proper pruning of hedges in the garden.
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Immune B Cells Found in the Meninges
The meninges (which contain large numbers of immune cells) and the cerebrospinal fluid (CSF) protect the brain from external influences such as trauma, and probably also play an important role in inflammation. Scientists have now investigated exactly which immune cells populate the meninges and the cerebrospinal fluid in healthy conditions.
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