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Nano-Capsules Could Trap and Disarm Viruses
To date, there are no effective antidotes against most virus infections. However, researchers have now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell cultures. It may also prove successful against corona viruses.
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mRNA Gets Its Close Up, Painting a New Picture of the Transcription Process
Scientists have discovered that the protein SPT6 is a central element in transcription. This finding has shown that the amount of RNA polymerases present to start transcription is not the only important factor in this process.
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Alternative-Splicing Regulator NSrp70 Influences Development of Immune T Cell
Scientists have explored the role of the protein NSrp70, abundant in motile T cells, and its encoding gene within a physiological environment to understand what part it might play in pathogen recognition and immunity.
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Analyzing DNA From Museum Specimens Reveals Evolutionary History
Museum specimens around the world contain a wealth of underutilized genetic information due to the poor state of DNA preservation, which often makes it difficult to sequence. Researchers have optimized a method developed for analyzing ancient DNA to identify the relationships between species on a deep evolutionary scale.
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Cell Communication Pathway Controlling Cell Growth and Survival Identified
Researchers have identified a cell communication pathway that is responsible for preventing overactivation of the insulin signal. The finding could eventually help to develop treatments for diseases such as cancer and diabetes.
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Bacteria Are Key to Vaginal Health
Bacterial vaginosis affects nearly 30% of women between the ages of 15 and 44. A study has discovered that members of the Veillonellaceae bacteria family cause changes that support bacterial vaginosis
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Isoflavone-Rich Diet Could Help To Protect Against MS Symptoms
A study suggests that the metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis, may provide protection against the disease.
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Body’s Reaction to Contact Allergens More Complex Than Previously Thought
About one in five Danes react to contact allergens, but some patients develop rashes and itching much faster than others. Previously the scientists were unable to explain why, but now researchers have outlined an entire new subgroup of allergic reactions which explains these early skin reactions.
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Simulations Reveal How Cyclic Peptides Diffuse Into Cells
Scientists have developed a computational method to predict the cell membrane permeability of cyclic peptides using a supercomputer. The approach could be a useful tool for the design and discovery of cyclic peptide drugs.
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Mechanical Stimuli Influence Organ Growth
Researchers have used organoids to investigate the effect of mechanical stimuli on organ growth.
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