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Proximal Tubule Cells Can Help or Hinder Kidney Repair
Researchers have shown that injured proximal tubule cells might contribute to the transition from an acute kidney injury to chronic kidney disease.
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Gene Profile in the Blood Predicts Worse COVID-19 Outcomes Before Patient Becomes Severely Ill
A blood gene profile associated with a high risk of dying from Idiopathic pulmonary fibrosis can also predict poor outcomes in patients with COVID-19.
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“Suffocating” Cancer: Preventing Diseased Cells From Thriving in Low Oxygen
A research group has used gene editing technologies to show how targeting Hypoxia Inducible Factor-1 alpha can inhibit tumor growth and drive cytotoxic immune cells to the cancer tissue.
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There’s More to Genes Than DNA, Mum and Dad Add Something Extra
Biologists at the Universities of Bath and Vienna have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science that describes how genes are switched on (and off) in different cells, at different stages in development and adulthood.
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Aging Speeded Up by Pollutant Exposure
Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards. This exposure can lead to free-radical production in our bodies, which damages our DNA and tissues. A new study suggests that unrepaired DNA damage can increase the speed of aging.
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Viral Infections Predicted by Microscopy Deep Learning
Researchers have shown for the first time that a machine-learning algorithm can recognize cells infected with herpes or adenoviruses based solely on the fluorescence of the cell nucleus.
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Cellular Mechanisms of Early Mammary Gland Development Unraveled
Researchers from the University of Helsinki have used live tissue imaging to visualize the emergence of the mammary gland.
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Impact of Silicone Breast Implant Surfaces on the Immune System Investigated
Researchers have systematically analyzed how the varying surface architecture found in breast implants influences the development of adverse effects, which in rare cases can include an unusual type of lymphoma.
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The Most Comprehensive RNA Atlas Ever
Researchers have built one of the most comprehensive catalogs of the human transcriptome ever.
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Immune Cell Swarming Behavior Unraveled
Using specialized microscopy for the real-time visualization of immune cell dynamics in living tissues, researchers have revealed how immune cells coordinate their swarming behavior to eliminate pathogens effectively together.
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