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Genetically Engineered Pigs and Chickens Provide Insights Into Health and Disease
Researchers have generated chickens and pigs in which target genes in desired organs can be efficiently altered to study molecular mechanisms of disease resistance or biomedical issues.
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Compound Found in Shrub Targets “Undruggable” Cancer Protein
A Purdue University chemist has discovered a way to synthesize a rare compound found in a shrub native to North America, to fight a previously "undruggable" cancer protein implicated in numerous cancer types.
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Research Reveals Distinct Types of Cells That May Be Involved in Breathing-Related Diseases in Infants
Recent research links certain cells that line the human airway with different infant diseases. The work could lead to new prevention and treatment strategies for these conditions.
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Factor in Psoriasis Episode Development Discovered
Scientists have identify a new factor in signal transmission of the immune system that plays a major role in the development of a psoriatic episode. The scientists have shown that symptoms can be alleviated by inhibiting the "c-Jun" protein in signal transmission.
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Immune Discovery Could Prevent Hemophilia Treatment Failure
Scientists have made a discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A.
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SARS-CoV-2 Variants From Mink Evade Inhibition by Antibody
Researchers have shown that an antibody used for COVID-19 therapy is unable to effectively inhibit SARS-CoV-2 harboring a spike mutation acquired in minks.
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Noncoding RNA’s Unexpected Journey in Making Memories
A new study has found that a long, non-coding RNA named ADEPTR has a central role in making memories.
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Distinct Goblet Cell Populations Identified
There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.
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Unique Mode of Cell Migration Revealed
Stanford engineers find that cancer cells exhibit a unique mode of migration on squishy materials, which are similar to biological tissues. In contrast, cell movement – a process central to cancer metastasis and other biological processes – is typically studied on very rigid materials.
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Climate and Human Land-Use Change Will Impact Genetic Diversity
Scientist present the first ever global assessment of how future climate and land-use will impact the genetic diversity of mammals, e.g. when tropical forests are converted to agricultural land.
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