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How Cells Control the Physical State of Embryonic Tissues
Understanding how cells act together to build tissues has been a fundamental problem in physics and biology. Researchers have now developed a computational framework that captures the various interactions between cells and connects them to embryonic tissue dynamics.
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What Spit Samples Can Tell Us About Pediatric OCD
Researchers at the University of Calgary and The Hospital for Sick Children (SickKids), in Toronto, have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth.
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Starving Brain Tumor Cells To Treat Medulloblastoma
Preclinical research using human tissue samples, human cell lines and mice has revealed that inositol hexaphosphate (IP6), a naturally occurring compound, inhibits medulloblastoma and can be combined with chemotherapy to kill tumor cells.
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Taiwanese Frog Species Found To Have Six Sex Chromosomes
Scientists found six sex chromosomes in the Odorrana swinhoana frog species endemic in Taiwan, giving new insights into how complex XY systems evolve.
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Adhesive Patch Delivers Blood Vessel-Forming Factors to Damaged Tissues
A research team has bioengineered a novel adhesive patch platform that can efficiently deliver blood vessel-forming growth factors using a bio-adhesive material that is made from mussels harmless to humans.
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Overfishing Has Not Caused Major Genetic Changes in Cod Populations
A "first-of-its-kind" study by researchers at Rutgers University and the University of Oslo has found that overfishing is not likely to be causing evolutionary changes and early maturation in the Atlantic cod fish population.
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CRISPRoff: A New Addition to the CRISPR Toolbox
Researchers have described a new gene-editing technology called CRISPRoff that allows researchers to control gene expression with high specificity while leaving the sequence of the DNA unchanged. The method is stable enough to be inherited through hundreds of cell divisions, and is also fully reversible.
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Brain Organoids Show How Viruses Can Impair Development
Researchers have demonstrated that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models.
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IL-33 Implicated in SARS-CoV-2 Immunity
Researchers have unveiled a novel feature of COVID-19 immunity, which could have implications for future therapies. The study points to the involvement of Interleukin 33 when immune cells encounter Sars-CoV-2 for a second time.
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New Method Advances Single-Cell Transcriptomic Technologies
Current single-cell transcriptomic methods put cells under stress, limiting accurate investigations. Scientists have now created the ACME method which fixes cells immediately, without cell dissociation, allowing for more accurate investigation.
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