News

A research team has identified and characterized a set of specific super-enhancers that stimulate the activity of related critical cancer genes. The research has also discovered that the deletion of certain specific super-enhancers can reduce tumor cell growth.

Researchers have exploited cryogenic electron microscopy to visualize mechanisms behind DNA damage, by illuminating the mysterious cycle of DNA breakage sensing and repair.

A study has shown that infection with parasitic intestinal worms (helminths) can cause sexually transmitted viral infections to be much more severe elsewhere in the body. According to the study, helminth-infected mice developed significantly more severe symptoms after infection with a genital herpes virus.

Researchers have successfully integrated human cells into animal tissue, producing human–monkey chimeric embryos that were able to grow for up to 20 days. The research, published in Cell, is a key step towards developing chimera-based tools for studying human health and disease, organ transplantation, drug discovery and many more research applications.

Clusters of norovirus are resistant to detergent and ultraviolet disinfection, according to new research. The work suggests the need to revisit current disinfection, sanitation and hygiene practices aimed at protecting people from noroviruses.

An observational study in nearly 20,000 individuals has found that greater intake of red and processed meat is associated with worse heart function.

Mammalian embryonic development is an extremely complex and precise process. Researchers have shown how the gene Dlx5 helps direct the generation of tissues in the head.

New research could help in the deployment of certain COVID-19 vaccines worldwide. Researchers have demonstrated a new, inexpensive technique that stabilizes lipid nanoparticles at room temperature for up to two months.

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.

Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a study by researchers at the National Institutes of Health.