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Elusive Inner Workings of Antioxidant Enzyme Revealed
Researchers from the University of Nebraska Medical Center (UNMC) and the Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) have now observed the complete atomic structure of an enzyme called manganese superoxide dismutaseMnSOD, including its proton arrangements, with neutron scattering.
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An XNA World Might Have Existed Before the RNA World
Nagoya University scientists in Japan have demonstrated how DNA-like molecules could have come together as a precursor to the origins of life.
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Breath Test Developed for Methylmalonic Acidemia
Researchers at the National Institutes of Health have developed a breath test that measures how well patients with methylmalonic acidemia (MMA) respond to receiving liver or combined liver and kidney transplantation. Researchers also used the test to assess the severity of the disease in people and help determine if they would benefit from surgical or experimental genomic therapies that target the liver.
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A Deep Dive Into the SARS-CoV-2 N Protein
Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein’s interactions with SARS-CoV-2 genetic material.
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New Method Sequences Small RNAs That Were Previously Undetectable
A team has developed a new RNA-sequencing method, called "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq, that can help discover numerous modified small RNAs that were previously undetectable.
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Ultrashort Peptides Make for a Cell-Friendly Biomaterial
A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.
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Nine Potential New COVID-19 Treatments
Scientists have discovered nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.
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Testicular Cancer May Be Associated With Exposure to Environmental Chemicals Suggests Canine Study
A new study investigates the association between the environment in which men live, their reproductive health and testicular cancer risk. The researchers looked at the effects of geographical location on polluting chemicals found in dog testes, some of which are known to affect reproductive health.
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“Nuclear Speckles” Inside Cells May Play a Role in Some Cancers
Scientists have shed light on the functions of mysterious structures in cells called "nuclear speckles", showing that they can work in partnership with a key protein to enhance the activities of specific sets of genes.
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New Generation of siRNA Could Enable New RNA Therapies
In a new study published in Cell Research, researchers at Nanjing University report that a new developments in synthetic biology could allow a type of gene therapy to acheive major therapeutic advances.
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