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Genetic Variant Puts Some Younger Men at Risk of Severe COVID-19

A new study of men with COVID-19 has allowed for the discovery of a genetic variant linked to disease severity. This could mean that men with severe disease may be genetically screened to identify who has the variant and may benefit from interferon treatment.
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Parkinson’s Gene Important for the Generation of Neurons Throughout Life

A gene defect linked to Parkinson’s disease may not only cause the early death of neurons, but also impair the process that generates neurons in the brain throughout our lifetime, a new study has revealed.
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How Human Cells Coordinate the Start of DNA Replication

Scientists have determined how origin Recognition Complexes assemble at the right time during the cell division cycle. One part of the complex is sequestered into small liquid bubbles, keeping it apart until the right time to recruit other proteins and initiate DNA replication.
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Protein May Play a Role in COVID-19 Clinical Variability

Why does COVID-19 seem to strike in such a haphazard way, sometimes sparing the 100 year old grandmother, while killing healthy young men and women in the prime of life? A new study by Karen Anderson, Abhishek Singharoy and their colleagues at the Biodesign Institute at Arizona State University, may offer some tentative clues.
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What Can Early-Budding Trees Tell Us About Genetics and Climate Change?

Understanding bud-break genetics enables scientists to modify or select crop varieties more resilient to threats such as climate change.
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Strong Coffee Shown To Increase Fat Burnt During Exercise

Scientists have shown that caffeine (about 3 mg/kg, the equivalent of a strong coffee) ingested half an hour before aerobic exercise significantly increases the rate of fat-burning. They also found that if the exercise is performed in the afternoon, the effects of the caffeine are more marked than in the morning.
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Do Ultra-Processed Foods Increase Heart Disease Risk?

A study found that higher consumption of ultra-processed foods may be associated with an increased risk of cardiovascular disease incidence and mortality, with each additional daily serving found to further increase risk.
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Ibuprofen Disrupts Key Protein Complex in Colorectal Cancer Cells

The mechanism behind the anti-tumor properties of NSAIDs has been largely attributed to the inhibition of cyclooxygenases, however, several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.
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Anti-Androgen Drugs May Disarm COVID-19 Spike Protein

Finding from a preclinical study suggest that anti-androgen therapies may help to disarm the coronavirus spike protein used to infect cells, by reducing androgen levels. Two receptors, ACE2 and TMPRSS2, are regulated by androgen and facilitate SARS-CoV-2's entry into host cells.
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Cellular Fingertips May Help Cells "Speak" to Each Other

What if you found out that you could heal using only a finger? It sounds like science fiction, reminiscent of the 1982 movie E.T. Well, it turns out that your body's own cells can do something similarly unexpected.
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