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Predicting Therapy Success With Individualized Models of Prostate Cancer
At present, drug response in cancer patients cannot be predicted. A research team has developed a new strategy for the generation of prostate cancer organoids that can contribute to the assessment of therapy response.
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Invasive Weed Could Help To Treat Cancer and Diabetes
An international team of scientists has discovered that extracts of a weedy grass called Andropogon virginicus appear to be effective against several human diseases, including diabetes and cancer.
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Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
The analysis of immune cells infiltrating cerebrospinal fluid enables the characterization of the tumor microenvironment in brain metastases. Findings confirm that these cells could act as novel and non-invasive biomarkers to predict patient responsiveness to immune-based therapies.
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Novel Inhibitor Shown To Combat Drug-Resistant Tumor Cells
A team of researchers from Martin Luther University Halle-Wittenberg and the University of Greifswald has developed a new inhibitor of multi-drug resistant protein 4 (MRP4). When the inhibitor was tested on drug-resistant cancer cell lines, the cancer cells began to respond to chemotherapy.
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New Study Predicts SARS-CoV-2 Evolving To Escape Current Vaccines
A new study of the U.K. and South Africa variants of SARS-CoV-2 predicts that current vaccines and certain monoclonal antibodies may be less effective at neutralizing these variants and that the new variants raise the specter that reinfections could be more likely.
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Today’s Humans Share Genes With Oceanic Creatures Missing Heads
The earliest multicellular organisms may have lacked heads, legs, or arms, but pieces of them remain inside of us today, new research shows.
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Gene-Editing Approach To Control the Invasive Gray Squirrel
A study published in Scientific Reports explores a novel combination of CRISPR‑based gene drives to control invasive gray squirrel – Sciurus carolinensis – in the UK.
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SARS-CoV-2 Variants Can Evade Antibodies That Neutralize Original Virus
New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.
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Gut Mycobiome Important in Processed Food Metabolism
Studies of the human gut microbiome focus mainly on bacteria. However, new research points to a significant role for fungi in the intestine — the communities of molds and yeasts known as the mycobiome — that are the active interface between the host and their diet.
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Dye Discovery Enables Scientists To Track Protein Within a Cell
Scientists have discovered a fluorescent chemical dye, making it possible for the first time to track the transport activity of a specific motor protein within a cell.
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