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Genetically Modifying Mosquitoes To Control the Zika Virus
Alexander Franz, an associate professor in the MU College of Veterinary Medicine, collaborated with researchers at Colorado State University by using CRISPR gene-editing technology to produce mosquitoes that are unable to replicate Zika virus and therefore cannot infect a human through biting.
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Antiviral Enzymes Convert Pre-Leukemia Stem Cells Into Leukemia
In response to inflammation, two enzymes called APOBEC3C and ADAR1 work together to trigger the transformation of pre-cancer stem cells to cancer stem cells in leukemia.
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Making Wheat and Peanuts Less Allergenic With Genetic Engineering
The United States Department of Agriculture identifies a group of “big eight” foods that causes 90% of food allergies. Among these foods are wheat and peanuts. Sachin Rustgi, a member of the Crop Science Society of America, studies how we can use breeding to develop less allergenic varieties of these foods.
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Circulating Myeloid Immune Cells Linked to Severe COVID-19
Patients with severe COVID-19 have significantly elevated levels of a certain type of immune cells in their blood, called myeloid-derived suppressor cells. The study may bring an increased understanding of how early immune responses impact disease severity.
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UK Will Offer Genomic Expertise To Find COVID-19 Virus Variants
The UK will offer its world-leading genomics expertise to identify new variants of the virus that causes COVID-19 to countries who do not have the resources to do so.
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Gut-Directed Astrocytes Dampen Inflammation in the Brain
Evidence has shown that astrocytes can also actively promote neurodegeneration, inflammation, and neurological diseases. Now, a team has shown that a specific astrocyte sub-population can do the opposite, instead serving a protective, anti-inflammatory function based on signals regulated by the bacteria that reside in the gut.
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Maternal Autoantibodies Highly Associated With Diagnosis of Autism
Using machine learning, researchers at the UC Davis MIND Institute have identified several patterns of maternal autoantibodies highly associated with the diagnosis and severity of autism.
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Cross Reactivity Seen Between SARS-CoV-2 and Antibodies to 2003 SARS Outbreak Virus
A new study demonstrates that antibodies generated by the novel coronavirus react to other strains of coronavirus and vice versa.
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Biologists Unravel the Mechanism of Break-Induced Replication
Break-induced replication (BIR) is a way to solve those problems. In humans, it is employed chiefly to repair breaks in DNA that cannot be fixed otherwise. A new study seeks to tease out BIR’s high risk-reward arrangement by describing for the first time the beginning-to-end sequence in BIR.
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Coconut Oil and Rapeseed Oil Treated Differently by the Liver
Coconut oil has increasingly found its way into kitchens in recent years, although its alleged health benefits are controversial. Scientists have now been able to show how it is metabolized in the liver. Their findings could also have implications for the treatment of certain diarrheal diseases.
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