News

Contrary to prior belief, certain T-cells remain in lymph nodes for a long time and store information about immune reactions there, reports a new study.

Researchers used gut organoids to perform a systematic CRISPR screening of 1800 human transcription factors and identified ZNF800 as a key regulator of the differentiation of a specific gut cell type, the enteroendocrine cells.

The UK regulatory authorities have approved the first ever trial of a revolutionary gene therapy for young children diagnosed with Hunter syndrome, a devastating rare lysosomal storage disorder.

Researchers made the breakthrough discovery that the genetically encoded T-cell receptor (TCR) sequence that humans develop in early childhood determines a T cell’s function.

Imaging technology developed at Garvan shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights for osteoporosis and cancer treatment.

Swapping a zinc ion for a cobalt ion to enhance the electric field at the active site of an enzyme increases its reaction speed so the enzyme can work 50 times faster than its unmodified analog.

The identification of a protein that regulates nutrient and water uptake in plant roots could help develop climate-proof crops that require fewer chemical fertilizers.

A recent discovery, published in PLoS Genetics, challenges the “rulebook” of DNA. We speak with the first author, Dr. Jamie McGowan, to learn about the accidental finding and what it means for synthetic biology.

Researchers from the University of Bergen (UiB) have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.

Researchers have unpicked the mechanism behind how Kaposi's sarcoma herpesvirus reprograms immune cells, increasing inflammation and making an individual vulnerable to cancer development.