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How SARS-CoV-2 Hijacks and Rapidly Damages Human Lung Cells
Scientists report the first map of the molecular responses of human lung cells to infection by SARS-CoV-2. By combining bioengineered human alveolar cells with precise mass spectrometry technology, researchers have identified host proteins and pathways in lung cells whose levels change upon infection by the SARS-CoV-2, providing insights into disease pathology and new therapeutic targets to block COVID-19.
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Protein Molecules Act as Mini Antennas Inside Cells
Researchers have demonstrated that molecules of fluorescent proteins act as antennas with optical properties. The newly described properties of these molecules could be harnessed for novel drug discovery and drug target research.
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Historical Bias Overlooks Genes That Are Related to COVID-19
Based on genome-wide experiments, the human body has 2,064 genes relevant to COVID-19. So why are researchers only studying 611 of them?
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Key Questions and Answers About the UK's First Approved COVID-19 Vaccine
The UK government has announced that the COVID-19 vaccine BNT162b2 – developed by Pfizer and BioNTech – has been authorized for use. Here, we address some of the key questions you may have about this announcement.
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Metabolic State of a Parasite Influences Its Resistance to Drugs
A new study has established that the parasite that causes chagas disease can be influenced by azole drugs, depending on its own metabolic state.
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CRISPR Tagging Improves Accuracy Of Model Cells Grown From Stem Cells
Researchers have found a way to program stem cells to differentiate into a particular cell type, using gene regulatory networks.
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Light Shed on Immune Mechanism That Triggers Cytokine Storms Typical of COVID-19
Researchers have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.
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Breaking Chemistry's Rules Unlocks a New Reaction
Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications – from creating new drugs to food production.
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Team Develops Transcription Factor Library for Cell Engineering
Scientists have discovered a way to extract large amounts of cells at a fast rate, using transcription factors.
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Researchers Edit Out an HIV-Like Virus From the Primate Genome
New research has brought scientists closer to curing HIV. SIV, a close relative of the virus has been successfully 'edited out' of infected cells in non-human primates.
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