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An Epaulette Shark crawls along an aquarium.
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Sharks’ Low Mutation Rate a Cancer Shield but a Survival Challenge

A Nature Communications study finds that epaulette sharks have the lowest mutation rate recorded in vertebrates. While this could shield the species from cancer, it may have detrimental effects on survival against environmental challenges.
Cells.
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Lung Cell Discovery May Have Implications for Cystic Fibrosis

A new study finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the opposite of what was expected of these cells.
A flowchart describing Antigen-positive tumor cells are a direct target of CAR T-cells due to high-affinity antibody-antigen contacts.
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“Switch” Identified That Activates Cancer Cell Death

A research team has identified a crucial epitope on the CD95 receptor that can cause cells to die. This new ability to trigger programmed cell death could open the door for improved cancer treatments.
T cells.
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Specialized T Cells Could Be the Culprit Behind Severe Asthma

Scientists have uncovered a group of immune cells that may drive severe asthma. These cells gather in the lungs and appear to possess the molecular weaponry to cause the most harm in men who developed asthma later in life.
Sweetener on a metal spoon.
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Could Artificial Sweeteners Have a Future in Autoimmunity Treatment?

A study raises the possibility that a common sweetener could suppress T-cell activation in humans, leading to potential therapeutic applications for managing diseases where excessive T-cell activation is problematic.
This illustration depicts a new platform for magnetic matrix actuation, enabling the study of how tissues respond to dynamic mechanical cues in their environment.
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Researchers Develop Gel “Exercise” Mat for Muscle Cells

The vibrating platform could be useful for growing artificial muscles to power soft robots and testing therapies for neuromuscular diseases.
A bandage pre-loaded with magnetic hydrogel placed on someones foot.
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Magnetic Gel Can Heal Diabetic Wounds Three Times Faster

A team of researchers engineered an innovative magnetic wound-healing gel that promises to accelerate the healing of diabetic wounds, reduce the rates of recurrence, and in turn, lower the incidents of limb amputations.
A neighborhood with green trees and an old car in the foreground.
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Beneficial Impacts of Greenspace Quantified at the Cellular Level

Living in a neighborhood with plenty of greenspace has a positive impact on telomere length – a marker of biological age – but this isn't enough to offset exposure to pollutants and other environmental challenges.
A plastic model of a brain and a brain cell.
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Converting Brain Immune Cells Into Neurons Helps Mice Recover After Stroke

Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice.
Stem cells.
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Study Reveals New Insights Into Postnatal Heart Cell Maturation

A team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, offering a deeper understanding of how heart muscle cells develop.
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