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How Do Cancer Cells Escape Crowded Tumors?

The mechanism enabling cells to evade crowded environments appears to involve an unusual player – the cell nucleus. This is what researchers from St. Anna Children's Cancer Research Institute Vienna, King's College London, Institute Curie Paris and ETH Zürich in Basel showed in their recent work.
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Immune Protein Orchestrates Symbiotic Relationship Between Bobtail Squid and Bacteria

New research revealed that, in the mutually beneficial relationship between with the Hawaiian bobtail squid, Euprymna scolopes, and the luminescent bacterium, Vibrio fischeri, an immune protein called “macrophage migration inhibitory factor” or “MIF,” is the maestro of daily rhythms.
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Memory Function Found in Natural Killer Cells

Scientists have managed to ascribe an immunological memory function to a subset of cytotoxic NK cells, which have hitherto been regarded as antigen-non-specific. These cells are therefore an interesting target for prophylactic use in the human immune system in the fight against infections and viruses.
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Trauma Impacts the Metabolism in Ways That Can Be Inherited, New Study Shows

How are signals triggered by traumatic events embedded in germ cells? A new study by Professor Isabelle Mansuy proposes a biological mechanism.
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After Cocaine Use, Astrocytes Build New Brain Connections

Researchers have tried to understand the formation of these memories in hopes of finding ways to disrupt them as a potential treatment for substance use disorder (SUD). A new study shows that cocaine use in mice leads to the formation of synapses by an unexpected architect: a type of cell called astrocytes.
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New Test Can Target and Capture Most Lethal Cells in Fatal Brain Cancer

A laboratory test developed by a research team led by Johns Hopkins University bioengineers can accurately pinpoint, capture and analyze the deadliest cells in the most common and aggressive brain cancer in adults.
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“Silent” Mutations Helped SARS-CoV-2 Thrive Once It Made the Leap to Humans

Researchers at Duke University have identified a number of “silent” mutations in the roughly 30,000 letters of the virus’s genetic code that helped it thrive once it made the leap to humans, and possibly helped set the stage for the global pandemic.
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Gel Instrumental in 3D Bioprinting Biological Tissues

Using a yield stress gel, Penn State engineers can place tiny aggregates of cells exactly where they want to build the complex shapes that will be necessary to replace bone, cartilage and other tissues.
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Genes That "Jump" May Rewire Neuronal Function in the Brain

A research team has used novel single-cell sequencing methods to analyze the expression of transposons in the brains of Drosophila melanogaster fruit flies. Their findings suggest that these "jumping" genes may rewire neuronal function in these somatic cells.
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Possible Breast Cancer Treatment for Patients With Specific Gene Mutations

Findings by Monash Biomedicine Discovery Institute (BDI) researchers have pointed to a new combination of treatments that may help breast cancer patients with certain gene mutations.
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