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Scientists Home In on How Cells Are Protected From Premature Aging

A new study by EPFL researchers shows how RNA species called TERRA muster at the tip of chromosomes, where they help to prevent telomere shortening and premature cell aging.
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Protein That Prevents Immune System Overreaction Could Have Therapeutic Applications

In a study published October 14, 2020 in the Proceedings of the National Academy of Sciences , researchers at University of California San Diego School of Medicine discovered that a molecule called Girdin, or GIV, acts as a brake on macrophages.
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Are Corals Genetically Prepared for Climate Change?

To shed light on whether Acropora corals are genetically equipped to handle a warmer ocean, researchers from OIST, the University of Tokyo and Seikai National Fisheries Research Institute have sequenced and analyzed the genomes of 15 species of Acropora coral, as well as three species of coral from outside this genus.
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Cancer-Killing T Cells “Swarm” Tumors Attracting Other Cells To Fight

The discovery of this swarming behavior of T cells, and the chemical attractants that immune cells use to direct swarms towards tumors, could one day help scientists develop new cancer therapies that boost the immune system.
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Protein Enabling Our Sense of Touch Also Informs Us That Our Bladder Is Full

A team co-led by scientists at Scripps Research has found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible.
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Scientists Begin To Unravel the Complexity of DNA Enhancers

In an attempt to learn more about DNA enhancers, the Crocker group from EMBL Heidelberg performed an extensive study, published in Nature, on a specific enhancer in the model organism Drosophila melanogaster, a species of fruit fly.
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Heart-on-a-Chip Gives Insights Into Cardioprotective Effects of Extracellular Vesicles

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences have unraveled potential mechanisms behind the healing power of extracellular vesicles and demonstrated their capacity to not only revive cells after a heart attack, but keep cells functioning while deprived of oxygen during a heart attack.
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Researchers Use Lab-Grown Tissue Grafts for Personalized Joint Replacement

A team led by Columbia Engineering has bioengineered anatomically precise living grafts for personalized replacement of a jaw joint, using the recipient's fat-derived cells, and demonstrated effectiveness in a clinically sized swine model.
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Problem Swine Coronavirus Has Human Infection Potential

New research suggests that a strain of coronavirus that has recently alarmed the swine industry may have the potential to spread to humans as well.
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How Cells Can Recover Their Longevity After Genome Damage

A research team from Cologne has discovered that a change in the DNA structure – more precisely in the chromatin – plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).
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