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A New Tagging System for Detecting and Purifying Proteins
In a study published in Frontiers in Plant Science, researchers from the University of Tsukuba, led by Professor Kenji Miura, have described a new tagging system for detecting and purifying proteins in plant cells.
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Epigenetic Drivers for Alzheimer’s Disease Discovered
New findings suggest that late-onset Alzheimer’s Disease is driven by epigenetic changes — how and when certain genes are turned on and off — in the brain.
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Killing Cancer Cells by Blocking Access to the Nucleus
Scientists have demonstrated that by blocking the construction of nuclear pore complexes it was possible to shrink aggressive tumors in mice whilst leaving normal cells unaffected.
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What Limits Immunological Memory?
After an infection occurs, the immune system will memorize the pathogen meaning it can react promptly if reinfection with the same pathogen should occur. Now, scientists have deciphered new details of this process.
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Exposing Cancer's Vulnerabilities Using Specialized Microscopy
Scientists seek insight into what makes its cells tick. Caltech researchers have shown that a framework they developed, using a specialized type of microscopy, enables them to probe the metabolic processes inside cancer cells.
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Stem Cells Repair Parkinson's-Affected Circuits in Mice
Stem cells, which are endlessly adaptable, have offered the promise of better neural repair. But the brain's precisely tuned complexity has stymied the development of clinical treatments. In a new study addressing these hurdles, University of Wisconsin-Madison researchers demonstrated a proof-of-concept stem cell treatment in a mouse model of Parkinson's disease.
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"Stretching Rack" for Cells Developed
The behavior of cells is controlled by their environment. Besides biological factors or chemical substances, physical forces such as pressure or tension are also involved. Researchers from Karlsruhe Institute of Technology (KIT) and Heidelberg University developed a method that enables them to analyze the influence of external forces on individual cells.
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Placenta Is Initiated First, as Cells of a Fertilized Egg Divide and Specialize
The first stages of placental development take place days before the embryo starts to form in human pregnancies. The finding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such as IVF, and a better understanding of placental-related diseases in pregnancy.
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Ribosomes Undergo a “Molting” Process, Shedding Their Layers
Maturation of the ribosome is a complex operation. Work by Ludwig-Maximilians-Universitaet (LMU) researchers now shows that the 90S precursor of the small 40S subunit undergoes a 'molting' process, during which it progressively discards its outermost components.
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A Real-Time Look at How Viruses Attack at the Single-Cell Level
A collaboration is on a mission to understand, in visual detail and with mathematical precision, all aspects of viral attack strategies, including how viruses invade host cell protein-making machinery.
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