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A New Target for Congenital Blindness Gene Therapy Is in Sight
Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, LMU researchers have now shown that targeted activation of genes of similar function can compensate for the primary defect.
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New Algorithm Reveals How Tumors Evolve During Their Lifetime
A new algorithmic approach reveals individual tumors continue to evolve and remodel their genomes, and this occurs across a broad range of tumor types. Identifying changes that benefit tumors and help them metastasize could help with future treatments.
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Studying How Cancer Cells Divide in Crowded Tumor Tissue
Scientists have studied how cancer cells are able to divide in crowded tumor tissue and have linked this to the hallmark of cancer progression and metastasis – the epithelial-mesenchymal transition (EMT).
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Reprogramming Yeast To Become a Mini Drug Factory
Stanford engineers have genetically reprogrammed the cellular machinery of yeast to create microscopic factories that convert sugars and amino acids into plant-based drugs.
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T Cells Can Become Memory Cells Before Even Meeting Their Foe
Memory cells remember previously encountered pathogens and help the body to react quickly and strongly when exposed to them again. However, the developmental process of strong immune cells that make these memory cells in advance without having to encounter the pathogens has now been discovered.
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Viruses on Glaciers Challenge Assumptions About Evolution
Scientists studying life on the surface of glaciers in the Arctic and Alps have shown that, contrary to expectations, the viruses on glaciers in the Alps, Greenland and Spitsbergen are remarkably stable in the environment, challenging assumptions on virus evolution.
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Venom From Honeybee Kills Breast Cancer Cells
A new body of work by scientists at the Harry Perkins Institute of Medical Research and The University of Western Australia demonstrates that honeybee venom induces cancer cell death in triple-negative breast cancer (TNBC) and HER-2 enriched breast cancer cells.
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Scent-Sensing Cells Have a Better Way To Fight Influenza
Researchers have reported on the remarkably robust immune response of olfactory sensory neurons, revealing a successful strategy against influenza infection.
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Cell “Suicide” Gene Further Linked to Immunotherapy Response
Researchers have added to evidence that a gene responsible for turning off a cell’s natural “suicide” signals may also be the culprit in making breast cancer and melanoma cells resistant to some immunotherapies.
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A Genetic Approach To Tackling Marine Biofouling
A group of synthetic biologists at NYU Abu Dhabi (NYUAD) have identified new genetic targets that could lead to safe, biologically-based approaches to combat marine biofouling – the process of sea-based microorganisms, plants, or algae binding to underwater surfaces.
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