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High levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2.

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

A new database of 40 breast cancer cell lines aims to help researchers deepen their understanding of these cell lines and speed up the development of new gene-targeted therapies.

Researchers have discovered how the communication between individual cells can be influenced with the help of a specific protein, which could have implications for the treatment of heart diseases.

New research has made an exciting leap forward in understanding how skin heals, which could lead to drug treatments to vastly improve wound healing.

Scientists have tracked down the rare stem cells that generate neutrophils in human bone marrow, providing a potential path for intervening in diseases where neutrophil development goes awry.

In Nature Communications, Fred Hutch scientists demonstrate in a mouse model how gene therapy could cure an infection that afflicts billions of people.

Genes that play an important role in allowing SARS-CoV-2 to invade heart cells become more active with age, according to research published in the Journal of Molecular and Cellular Cardiology.

Bioengineers and surgeons from Rice University and Baylor College of Medicine (BCM) have shown that shielding stem cells with a novel biomaterial improves the cells' ability to heal heart injuries caused by heart attacks.

Alternative carrier-free systems, known as nanoprodrugs (NPD), show immense promise for cancer treatment. Now, researchers have carried out a study on the dynamics of SN-38 NPDs inside cancer cells, looking specifically at their internalization rate, intracellular localization and degradation, as well as their therapeutic efficiency.