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Genome-wide CRISPR Technology Hunts for Leukemia’s Weakness
A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.
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Stabilizing a Key Braking Mechanism in Cancer
Researchers have identified a binding site where drug compounds could activate a key braking mechanism against the runaway growth seen in many types of cancer.
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Stem Cells in Human Embryos Commit to Specialization Surprisingly Early
The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by researchers at the Francis Crick Institute.
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New Ways To Understand How SARS-CoV-2 Is Evolving
A new study has unlocked a novel way to understand evolving strains of SARS-CoV-2, which could help to identify new clusters of the virus.
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Study Points to Existence of a Lipid Code
Researchers have developed chemical tools that can be used to influence lipid concentration in living cells, the results from which indicate a “lipid code”.
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Evidence for Existence of Elusive “Metabolon”
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or “metabolons,” in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers at Penn State, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular metabolites.
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Simulations Illustrate How To Make Gene Therapy More Effective
Scientists at the University of Groningen have now used advanced simulations to investigate how lipoplexes deliver DNA fragments into cells. The results, which were published in the journal eLife, can be used to improve their efficiency.
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Decoy Proteins That Bind and Trap the Coronavirus in Development
Decoy proteins that bind and trap the coronavirus to stop it infecting cells in our bodies are being developed by the University of Leicester.
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New "Toolbox" for Urological Cancer Detection
Researchers have developed a new method for biomarker discovery of urological cancers, which enables timely diagnosis and treatment of cancer.
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Protein Offers a Hand in Fertilization
In a recent study, researchers from Osaka University and Baylor College of Medicine have identified a novel protein that takes part in sperm-oocyte membrane fusion during fertilization, and named it Fertilization Influencing Membrane Protein (FIMP).
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