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Keys with the DNA bases written on them in a random order.
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Understanding Bacteria on an Individual Level

Recently, scientists have begun leveraging next-generation sequencing and associated techniques, such as single-cell RNA sequencing, that researchers can use to study gene expression in hundreds of thousands of individual cells simultaneously.
 Stress Fibers and Microtubules in Human Breast Cancer Cells.
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Preventing Stiffness May Slow the Progression of Breast Tumors

A study demonstrates that laminin prevents the effects of stiffening, protecting cells against tumor growth. While the mechanism has been demonstrated in vitro, persuasive indications suggest its potential applicability in vivo.
A blood vessel with red blood cells travelling.
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A Novel Principle for Nitric Oxide-Mediated Signaling in Blood Vessels

Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels. Researchers now present a novel principle that challenges the previous hypothesis.
Someone placing their hands on their stomach.
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Driver of Inflammatory Bowel Disease Identified

Researchers have discovered an intracellular mechanism that converts protective intestinal cells into disease-driving pathogenic cells, a finding that could lead to improved treatments for patients with inflammatory bowel disease (IBD).
A 3D model of a human brain with coloured string emitting from the sides.
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New Insights on Fear Memory Formation Could Inform PTSD Treatment

Cerebellar inhibitory interneurons are essential for fear memory, a type of emotional memory formation. Inhibitory interneurons within the cerebellar circuitry act as gatekeepers and control the output of the cerebellar cortex.
Protein chains.
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AlphaFold Analyzes Millions of Predicted Protein Structures

By developing an efficient way to compare all predicted protein structures in the AlphaFold database, researchers have revealed similarities between proteins across different species.
Dark green leaves.
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Plant Compound Inhibits Candida Fungi

A natural compound in many plants has been found to inhibit the growth of drug-resistant Candida fungi, including the most virulent species.
This digitally-colorized, negative-stained transmission electron microscopic (TEM) image depicted a number of Influenza A virions.
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Triggers for Development of Lung-Resident Memory B Cells in Influenza Infection Identified

Lung-resident memory cells are critical for pulmonary immunity. The pathway by which they develop following influenza infection has now been identified.
Plants with brown spots on them.
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The Bacterial Killer Cocktail That Hijacks Plant Cells

Many of the bacteria that ravage crops and threaten our food supply use a common strategy to cause disease: injecting a cocktail of proteins directly into the plant’s cells. Now researchers may finally have an answer to how this makes plants sick.
Confocal image of a CHOOSE (CRISPR-human organoids-scRNA-seq) human brain.
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How Human Brain Organoids Are Uncovering the Cause of Autism

With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.
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