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Novel Mechanism in Childhood Kidney Cancer
To execute their respective manuals, cells employ "chromatin reader" proteins that identify which gene is up for expression. Now a new study has found that an issue in this gene-regulatory process may cause normal cells to turn malignant resulting in a Wilms' tumor, the most common kidney cancer in children.
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Novel Protein Discovery Yields Viral Infection Insights
Researchers have discovered a protein that can enable adenoviruses to infect human cells; this knowledge could be used to protect those with weakened immunity against dangerous viruses.
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Functional "Mini-liver" Created by 3D Bioprinting
Using human blood cells, researchers have succeeded in obtaining “mini-livers” that perform all of the liver’s typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others. The innovation permits the production of hepatic tissue in the laboratory in only 90 days and may in the future become an alternative to organ transplantation.
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Blue Mushroom Dye Used To Develop New Bioimaging Tool
A new fluorescent tool for detecting reactive oxygen species based on a chemical found in mushrooms has been developed by scientists at the University of Bath.
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What Happens to Gold Nanoparticles in Cells?
Contrary to previous thought, a study has revealed the ability of cells to metabolize gold nanoparticles, which are frequently used in cell imaging.
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How Cells Get Moving
Researchers have identified the proteins that are essential for the assembly of structures needed for cell movement.
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Scientists Take Stem Cells and Convert Them to Heart Pacemaker Cells
Researchers are helping usher in a new age of cardiac pacemakers by using stem cells found in fat, converting them to heart cells, and reprogramming those to act as biologic pacemaker cells.
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Using Genetic Tools To Treat Little Hearts
A team of researchers has discovered a new mechanism involved in a common congenital disease of the aortic valve.
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Battling Antibiotic Resistance With CRISPR
A research team led by Andrés Valderrama at UC San Diego School of Medicine and Surashree Kulkarni of the Division of Biological Sciences has developed a new CRISPR-based gene-drive system that dramatically increases the efficiency of inactivating a gene rendering bacteria antibiotic-resistant.
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Mapping Circular DNA in Childhood Cancer
An international team of researchers has revealed that mysterious rings of DNA called "extrachromosomal circular DNA" is linked to cancer development in children.
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