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New Drug Combo Could Work Against Broader Array of Cancer Cells
Researchers have discovered two drugs that work together to disrupt cancer cells’ ability to survive.
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Cell Family Trees Tracked To Discover Their Role in Liver Disease
Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.
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Revival of 50,000-Year-Old Gene Reveals How Deadliest Malaria Parasite Jumped From Gorillas to Humans
In a study published today in PLOS Biology, researchers from the Wellcome Sanger Institute and the University of Montpellier have reconstructed a ~50,000-year-old gene sequence acquired by the ancestor of Plasmodium falciparum. The acquisition of the gene sequence enabled the parasite to infect human red blood cells.
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Microbiome Is Shaped by Genetic Differences in the Immune System
Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.
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New Genetic Engineering Tool Opens Floodgates of Microbial Metabolite Applications
A team of microbiologists and genomicists led by the Department of Energy Joint Genome Institute (JGI) has invented a genetic engineering tool, called CRAGE, that could not only make studying microbes much easier, but also fill significant gaps in our understanding of how microbes interact with their surroundings and evolve.
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Reducing Heart Attack-induced Tissue Damage by 30%
Scientists have discovered that inhibiting the synthesis of a lipid in a mouse suffering a heart attack reduces the tissue damage by 30%.
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It's Time To Keep Check on the Microbiome
Scientists have developed a novel technique based on an oscillating gene circuit that they hope will help to shed light on the human microbiome.
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Powerful Technique Tracks Down Genetic Disease
A team led by a scientist at Scripps Research has invented a new genomics technique for tracking down the causes of rare genetic diseases. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.
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Ethics of Ancient DNA
In recent years, the study of ancient DNA, also known as aDNA, has rapidly advanced, providing important insights into a range of biological, historical, and social questions. The National Science Foundation has awarded a $350,882 collaborative grant to an array of institutions to analyze the current ethical landscape of ancient DNA research.
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When Studying Immune Cells, Environment Matters
A new report recommends that looking outside the dish and into living organisms gives an improved understanding of the way immune cells process and use energy.
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