New Approach Enables Ultra-Sensitive Exosome Biosensing
Circulating tumor exosomes are composed of molecules that reflect the parental cells. But, because they are tiny and complex, the precise detection of exosome-carried biomarkers with molecular specificity has so far been difficult.
Humans and Chimpanzees Use a Part of Their DNA in Different Ways
Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a difference which, despite all our similarities, may explain why our brains work differently.
Drug Target for Parkinson’s Disease May Not Be Relevant for All Patients
A new study conducted using mice suggests that targeting the alpha-synuclein protein may not be sufficient to treat the disease and alleviate symptoms in most patients.
New Insights Into the Cellular Basis of Cystic Fibrosis
Researchers are hopeful that new understanding of cellular defects related to cystic fibrosis could help pave the way for treatment of the disease.
Stem Cell Population Identified That Is Key for Bone Regeneration
Researchers have identified a subpopulation of MSCs that promote the healing of bone fractures and show an enhanced ability to differentiate into various cell types.
APOE4 Linked With Better Visual Working Memory in Older Adults
A well-known gene that increases Alzheimer’s risk, called APOE4, has been linked with better visual working memory in older adults.
Biological Clock Assembled in a Test Tube To Study How It Works
A team of scientists has reconstituted the circadian clock of cyanobacteria in a test tube, enabling them to study rhythmic interactions of the clock proteins and understand how these interactions enable the clock to exert control over gene expression.
Some Gut Bacteria Fuel Prostate Cancers and Drive Treatment Resistance
A new study has found that common gut bacteria can fuel the growth of prostate cancers and allow them to evade the effects of treatment.
How Two Meters of DNA Is Packaged Into a Human Cell
How is two meters of DNA packed into the tiny nucleus of a cell? Scientists have uncovered the molecular processes by which a complex of proteins act as the "Marie Kondo" of molecular biology, folding DNA into neat loops.
Boosting the Cell's Power House
Using cryo-electron microscopy, a technique that allows researchers to look at extremely small samples in their natural state, researchers have shown the exact structure of the so-called supercomplex CIII2CIV.