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Solved: 50-Year-Old Mystery of How Nature Produces Bioactive Chemical Compounds
Research led by the University of Michigan Life Sciences Institute has solved a nearly 50-year-old mystery of how nature produces a large class of bioactive chemical compounds - prenylated indole alkaloids.
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Study Explores Integrity of Research Specimens
Biological samples can be highly susceptible to changes over time, and degraded samples can produce spurious results in research. To address these concerns, scientists have designed a highly sensitive test that can be used to establish the integrity of blood plasma and serum, the most common biosamples used in medical research.
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Pinpointing DNA Differences Between Immune Diseases
Research has shown that thousands of differences in DNA between individuals, associated with immune diseases, are linked with the switching-on of a specific subtype of immune cells.
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Catalyst Destroys Cancer Cells’ Essential Energy Source
Scientists have developed a technique that uses light to activate a cancer-killing compound of Iridium that attacks an essential energy source in cancer cells, even under hypoxia.
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Better Delivery Within the Brain by Utilizing LAT1
The distribution of drug molecules within the brain can be enhanced by utilizing LAT1, according to a new study.
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First-of-Its-Kind Epigenetic Study Links Excessive Oxytocin Levels With Hypersexuality Disorder
A new study of men and women with hypersexual disorder, also known as compulsive sexual behavior, or "sex addiction", suggests a role for the hormone oxytocin in its pathophsiology.
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Disproving the Prevailing Theory of How DNA Binds Itself
Researchers disprove the prevailing theory of how DNA binds itself. It is not, as is generally believed, hydrogen bonds which bind together the two sides of the DNA structure. Instead, water is the key. The discovery opens doors for new understanding in research in medicine and life sciences.
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World's First Laser Incubator for Blood Developed
Researchers have developed the world's first blood incubator using laser technology. This could prevent fatal blood transfusions in critically ill patients, and can detect antibodies in pregnant women that can kill a foetus.
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Rethinking How Cholesterol Is Integrated Into Cells
In an international collaboration, researchers from Aarhus University have presented a completely new, ground-breaking model for the integration and incorporation of cholesterol into cells, with great impact on our understanding of this important process.
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How Cells Maintain Their Identity
In the body's cells, some proteins are of vital importance as to which genes are active or turned off. Now, researchers from the University of Copenhagen and the Memorial Sloan Kettering Cancer Center have discovered which proteins are necessary in order to maintain the proper genetic regulation.
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