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A microscope lens focusses on a slide.
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New Tool Aligns Data From Tissue Slices Virtually, Expanding Possibilities for 3D Analysis

A new tool that can align data from slices of tissue to discern the 3D makeup of the tissue could allow for a much deep understanding of tissue biology.
A man yawning.
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Astrocytes May Be the Key to Staying Awake Without Getting Tired

New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences.
The three-armed structure of PIEZO1.
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How PIEZO1 Changes Shape in Response to Mechanical Stimuli

The ability to sense mechanical stimuli, like touch or blood pressure, is essential to physiological processes in humans. New research has revealed critical information about how the sensory ion channel PIEZO1 changes shape to function.
Human iPS cells.
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New Method Developed To Reprogram Human Cells

Researchers have developed a new method to reprogram human somatic cells to mimic embryonic stem cells better, with significant implications for biomedical and therapeutic uses.
Representation of stem cells.
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Connective Tissue Cells Reprogrammed Into Muscle Stem Cells Without Genetic Engineering

A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases – and for those who would like to eat meat, but don’t want to kill animals.
Several cells shown in high resolution, against a black background.
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Fast Super-Resolution Imaging Achieved Over a Wide Field of View

A new fluorescence microscope has enabled fast, super-resolution imaging of live cells over a wide field of view.
An octopus.
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Using an Octopus Brain To Understand Memory

Researchers have uncovered the neural architecture governing the learning processes of the enigmatic Octopus vulgaris. The research presents a promising model for studying memory networks.
Imaging of neural stem cells.
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Genetically Modified Neural Stem Cells Show Potential for Spinal Cord Injuries

A research team has recently made a significant advancement in spinal cord injury treatment by using genetically modified human neural stem cells.
Organelles in a cell.
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Formation of Molecular Aggregates Observed in Living Cells for the First Time

Using a newly developed microscopy method, researchers have been able to quantify how small, dynamic molecular aggregates form in living cells for the first time. Such aggregates play an important role in signal processing.
Cells with organelles visible inside.
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Protein Explains How Part of the Nucleolus Evolved

A single scaffold protein is critical for the formation of part of the nucleolus, giving clues to how the nucleolus evolved around 300 million years ago.
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