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Cinnamon Vape Flavor Most Damaging to Human Stem Cell-derived Endothelial Cells
The effect of flavored e-cigarette liquids on endothelial health and macrophage activation was assessed in a study of human stem cell-derived endothelial cells.
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DNA Nanostructures Capable of Self-healing
DNA assembled into nanostructures such as tubes and origami-inspired shapes could someday find applications ranging from DNA computers to nanomedicine. Now, researchers have designed DNA nanostructures that can heal themselves in serum.
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Genetic “Switch” Helps Breast Cancer Spread
Researchers have unveiled clues into how breast cancer cells spread around the body. The team identified a genetic ‘switch’ in breast cancer cells that boosts the production of a type of internal scaffolding.
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A Blueprint for Guiding Animal Genomics Forward
Researchers have designed a new vision for animal genomics research into the next decade. The blueprint they created could help scientists and farmers meet the needs of a growing global population while improving livestock welfare and production.
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Progress in the Hunt for Drugs Targeting Unwanted Autoimmunity
Inhibiting an enzyme called cyclic GMP-AMP synthase could stop an unwanted cascade of cellular signaling events that occurs during autoimmune diseases.
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More “Risk” Genes Added to the List for Alcohol Use and Abuse
A genome-wide association study has identified five new genetic risk loci that can pass on risk for harmful alcohol use from parents to children, and confirmed one previously identified risk locus.
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Prostate Cancer Cells Mimic Bone-forming Cells When They Metastasize
Prostate cancer cells develop the ability to mimic bone-forming cells called osteoblasts, enabling them to proliferate in the bone microenvironment –researchers describe how in a new study.
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First Large-scale Genetic Analysis of the Human Plasma Lipid Species
Understanding the genetics of lipid species offers information beyond that provided by routine lipid screening, and can help improve risk prediction and treatment. In the first large-scale study, novel lipid-associated genetic variants were identified, some of which were linked with risk for cardiovascular disease, such as heart attacks and strokes.
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Cancer Cells: Quick-change Artists Adjusting to Their Environment
Scientists now show that cancer cells of glioblastomas – conspicuously aggressive solid brain tumors – manifest developmental plasticity and their phenotypic characteristics are less constrained than previously believed.
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Virus's Coat of Deadly Armor
Viruses interact with proteins in the biological fluids of their host resulting in a layer of proteins on the viral surface. This makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer's disease.
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