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Accumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the latter, ribosomal proteins (green fluorescent) and the size of nucleoli (red) are increased.
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“Junk Proteins” Associated With Cause of Aging and ALS Progression

CNIO researchers provide a new hypothesis to understand the origin of amyotrophic lateral sclerosis, or ALS. It would be triggered by a similar problem to that occurring in a group of rare diseases called ribosomopathies.
Three X-shaped chromosomes.
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A New Technique for Creating Artificial Human Chromosomes

A new quick and precise technique for producing artificial human chromosomes has been developed, which could be used to power advanced gene therapies.
Bacteria growing on an agar plate.
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Candida albicans Toxin's Role in Digestive Tract Colonization

A team has now discovered that the toxin Candida albicans also plays an important role in the colonization of the digestive tract.
A 3D model of a human brain.
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Study Reveals Key Role of Immune Cells in Alzheimer's Disease

The Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain immune cells, microglia.
A woman holding her stomach in pain.
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Endometriosis: What’s the Latest Research?

Endometriosis represents a multifaceted challenge affecting millions of individuals globally. Recent studies have massively advanced our understanding of how the condition affects individuals and is helping to improve the lives of those affected.
Cancer cells.
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Evolution of Urinary Tract Cancer Cells Mapped

Researchers at Weill Cornell Medicine have performed the most comprehensive analysis to date of cancer of the ureters or the urine-collection cavities in the kidney, known as upper tract urothelial carcinoma (UTUC).
Cells.
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Microfluidic Technology How Individual Cells Respond to Viral Infection

A team of scientists from Montana State University recently published unique research examining how individual cells respond to viral infection. The work used state-of-the-art technology to culture cells and track infection in real time.
A bar chart on top of a mountain scene.
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New Method Identifies Extremophiles Using Protein Fragments

Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth.
A newborn baby.
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Why Are Newborns Susceptible to Severe Infections?

A new study of mice by Columbia University researchers now suggests that many cases of neonatal neutropenia may originate from suppression of the fetus’s blood-forming stem cells.
The adult midgut of the Drosophila fly.
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Fruit Fly Research Unveils Adhesion GPCR’s Role in Gut Development

Adhesion GPCRs are a group of G protein-coupled receptors associated with many bodily functions and diseases in humans. Scientists discovered a new receptor that influences the development of the small intestine and heart function in fruit flies.
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