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Gene Associated with Erectile Dysfunction Identified
In a new study that ultimately analyzed the genomes of nearly a quarter of a million men, a research team including UC San Francisco scientists has discovered that variants at a single site on Chromosome 6 are associated with a significantly higher risk of developing erectile dysfunction (ED).
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Spatiotemporal Self-patterning of Stem Cells Interrogated with CRISPR
Understanding how physical organization of cells influences their identity is necessary for creating better organoids.
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Know Your Enemy
To fight your enemies, it helps to know their weaknesses. And, the more specific your knowledge, the easier it is to undermine their defenses - this includes bacteria.
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Paralysis from Rare Disorder: Stem Cell Therapy Trial Brings Hope
A clinical trial is planned to see if a single injection of progenitor cells can help repair spinal cords inflamed by transverse myelitis.
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CRISPR Heals Mouse Genomic Disease
A team of researchers from ETH Zurich and the University Children’s Hospital Zurich applied a newly developed editing tool to target and correct genetic mutations. By doing so, the researchers healed mice suffering from a genetic metabolic disorder that also affects humans.
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Why Sharks are Genomic "Living Fossils"
Scientists have decoded the whole genomes of two shark species for the first time and improved the whale shark genome sequences released previously. By analyzing the genomes and comparing them with those of other vertebrate species, they have constructed an overview of their unique life histories and evolutionary paths.
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Immune System "Brake Failure" Could Contribute to Diabetes
In the rodent form of type 1 diabetes, specific immune cells fail to respond to one of these checkpoint molecules, letting the immune system go into overdrive and attack insulin-producing cells.
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Implantable, Biodegradable Electrodes Speed Up Neural Regeneration
Scientists have developed a implantable, biodegradable device that delivers regular pulses of electricity to damaged peripheral nerves in rats, helping the animals regrow nerves in their legs and recover their nerve function and muscle strength more quickly.
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Epigenetic Profiling Improved by Using Enzyme, Rather than Chemical, Deamination
A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases.
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Human Nucleoli Behave as Liquid Droplets
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components.
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