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Fully Automated Algorithm for NGS-Based Clonality Testing
Researchers develop objective criteria, which can be automated, to classify B and T cell clonality results as positive (clonal), no evidence of clonality or invalid (failed).
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Fast and Effective Method to Genetically Modify Brain Organoids Developed
Researchers have now succeeded in genetically manipulating brain organoids in only a few days instead of the usual several months.
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Air Pollution Particles Trigger Autophagy
New research from the Keck School of Medicine of USC shows that air pollution particles activate a cellular defense mechanism known as autophagy, which may reduce the ability of cells to fight off other harms.
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Human Immune Cells React to Non-Nutritive Sweeteners
Non-nutritive sweeteners, commonly used in diet drinks, have been shown to impact gene expression in white blood cells, which researchers suggest may sensitize the immune cells to certain stimuli.
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Recipe for Making Blood Vessel Cells From Patient Stem Cells Published
Researchers have published a detailed protocol for making vascular endothelial cells, pericytes and fibroblasts from human induced pluripotent stem cells.
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New Test Measures Cell Mechanotypes Quickly and Easily
In a promising development for cancer screening and treatment, groundbreaking research has led to a new laboratory test to measure cell mechanotypes quickly and easily.
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AI Tool Enables Quick and Reliable Imaging of Proteins in Cells
Max Planck researchers programmed a tool that accurately recognizes and picks proteins in electron cryo-tomography, substituting troublesome hand selection.
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Severe Hot Flashes After Menopause Associated With Increased Metabolic Syndrome Risk
Women who experience more severe hot flashes after menopause are more likely to develop metabolic syndrome and high blood pressure. The findings of this long-term study highlight the importance of using hormone replacement therapy for menopause in these women.
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New Insights Into Natural Product Biosynthesis Revealed
Single-cell multiomics reveals that cell types are differentially involved in the production and accumulation of medically relevant plant compounds.
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Proteomic Approach Identifies Contents of p62 Bodies
Scientists use a novel technique to identify a protein complex degraded by autophagy with a possible role in liver cancer.
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