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Genetic Link to Malfunctioning Bone Marrow Cells Identified

News   Aug 24, 2018 | Original story sourced from Cincinnati Children's Hospital

 
Dysregulated HIF1A Gene Responsible for Some Bone Marrow Disorders

This microscopic image of myeloid cells taken from a genetic mouse model shows signs of the blood disease MDS (myelodysplastic syndromes), which can lead to leukemia. Instead of the normal appearance of myeloid blood cells—a smooth, round, donut-shape with a single nucleus—cells with MDS are underdeveloped, have multiple nuclei or are hyper-segmented. Credit: Cincinnati Children's Hospital

 
 
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