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How the Cellular Recycling System Is Put on Hold While Cells Divide

News   Nov 14, 2019 | Original story from the Babraham Institute

 
How the Cellular Recycling System Is Put on Hold While Cells Divide

HeLa cells stained with an antibody for ATG13 (green), which marks 'autophagosomes' the cell's recycling factories. They are also stained with a dye called DAPI, which marks DNA (blue). These cells have been starved of amino acids; this activates autophagy, causing the assembly of autophagosomes, which are seen as discrete green dots. The two highlighted cells are in mitosis (their chromosomes have condensed and are clearly seen in blue); these cells exhibit few or no green dots indicating that autophagy has been repressed in cells undergoing mitosis. Credit: Cook lab, Babraham Institute

 
 
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