Nuvo Research Announces Scientific Presentation at the Annual Meeting of AAI
News May 17, 2013
Nuvo Research Inc. has announced that researchers from the Fraunhofer Institute for Cell Therapy and Immunology IZI and Nuvo presented scientific data related to WF10's therapeutic impact on signs and symptoms of experimentally induced rheumatoid arthritis in mice at the 100th Annual Meeting of The American Association of Immunologists (AAI) in Honolulu, Hawaii, U.S.
Compared to the placebo group, animals treated with WF10 showed a reduction of the degree of symptoms. Based on these results, the investigators concluded that WF10 may present a novel therapeutic approach for patients suffering from rheumatoid arthritis and other inflammatory autoimmune diseases.
Rheumatoid arthritis is a complex chronic autoimmune disease and the most common inflammatory disorder of joints leading to cartilage destruction, bone erosion and deformation of joints.
The initializing causes of rheumatoid arthritis are not fully understood and thus there can be no guarantee that the results observed in this animal model will be reproducible in humans.
"This joint poster presentation is a result of the deep and fruitful cooperation between Nuvo and the prestigious Fraunhofer Institute in Leipzig, Germany," said Dr. Henrich Guntermann, Nuvo's President, Europe and Immunology Group.
Dr. Guntermann continued, "With our partners in Leipzig and supported by funding from the Development Bank of Saxony (SAB) and the European Fund for Regional Development (EFRE), we are currently working on multiple research and development projects to further explore WF10's full potential."
Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes.READ MORE