Self-Assembling, Biomimetic Membranes May Aid Water Filtration
News Aug 03, 2015
This biomimetic membrane is composed of lipids -- fat molecules -- and protein-appended molecules that form water channels that transfer water at the rate of natural membranes, and self-assembles into 2-dimensional structures with parallel channels.
"Nature does things very efficiently and transport proteins are amazing machines present in biological membranes," said Manish Kumar, assistant professor of chemical engineering, Penn State. "They have functions that are hard to replicate in synthetic systems."
The researchers developed a second-generation synthetic water channel that improves on earlier attempts to mimic aquaporins – natural water channel proteins -- by being more stable and easier to manufacture. The peptide-appended pillararenes (PAP) are also more easily produced and aligned than carbon nanotubes, another material under investigation for membrane separation.
"We were surprised to see transport rates approaching the 'holy grail' number of a billion water molecules per channel per second," said Kumar. "We also found that these artificial channels like to associate with each other in a membrane to make 2-dimensional arrays with a very high pore density."
The researchers consider that the PAP membranes are an order of magnitude better than the first-generation artificial water channels reported to date. The propensity for these channels to automatically form densely packed arrays leads to a variety of engineering applications.
"The most obvious use of these channels is perhaps to make highly efficient water purification membranes," said Kumar.
Computation and Chemistry Combine to Create World-First Auxetic ProteinNews
A team of chemists at the University of California, San Diego (UCSD) has now designed a two-dimensional protein crystal that toggles between states of varying porosity and density. This is a first in biomolecular design that combined experimental studies with computation done on supercomputers. The research, published in April 2018 in Nature Chemistry, could help create new materials for renewable energy, medicine, water purification, and more.
Fructose Formula Poses Risk to Babies With Metabolic DisorderNews
Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Baby formula manufacturers should remove fructose or sucrose, or explicitly label their products to allow parents to avoid those sweeteners if necessary, the doctors say.
Abzena Selects Sartorius Stedim Biotech to Equip its US Based Development and Manufacturing SitesNews
Abzena plc, the life sciences group providing services and technologies to enable the development and manufacture of biopharmaceutical products, has selected Sartorius Stedim Biotech as its preferred equipment supplier in the U.S.READ MORE
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