Stem Cell Innovations Signs Compound Validation Collaboration with H. Lundbeck
News May 10, 2007
Lundbeck is a research-based pharmaceutical company, engaged in research to find new drugs for treatment of CNS disorders.
“This new collaboration shows the expanding acceptance of our C3A cell-line as an excellent platform to study human liver function,” said Stem Cell Innovations’ CEO Dr. James Kelly.
“Our protected C3A cell system has intact human liver machinery, is robust and thoroughly quality controlled, all the prerequisites for larger scale in vitro efficacy and safety programs,” Kelly added.
C3A is SCI’s patented human liver cell line, originally developed for use in an artificial liver used to support patients waiting for transplantation. The cells exhibit a wide variety of human liver functions and are ideal for use in examining the effects of new drugs on the human liver.
The application of SCI’s ACTIVTox system, based on the C3A cell line, can lead to better drugs with a decreased likelihood of causing liver toxicity.
A research team developed a microfluidic-based drug screening chip that identifies synergistic interactions between two antibiotics in eight hours. This chip can be a cell-based drug screening platform for exploring critical pharmacological patterns of antibiotic interactions, along with potential applications in screening other cell-type agents and guidance for clinical therapies.READ MORE