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Is Ridding Cells of Stress Granules the Answer to Ataxia?

News   Sep 10, 2018 | Story sourced from the University of Utah Health

 
Stifling 'Staufen1' in Cells Improves Motor Function in Neurodegenerative Mice

Co-localization of Staufen1 with ATXN2 in stress-granule-like structures. ATXN2 and STAU1 co-localize in stress granules. Immunostaining of HEK-293 cells with antibodies against ATXN2, STAU1, and TIA-1 show co-localization of STAU1 with ATXN2 and TIA-1 in SGs during stress (0.5 mM sodium arsenite for 15 and 30 min) that are not present in the absence of stress. Scale bar, 10 µM. Credit: Paul et al 2018.

 
 
 

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