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Is Ridding Cells of Stress Granules the Answer to Ataxia?

News   Sep 10, 2018 | Story sourced from the University of Utah Health

Stifling 'Staufen1' in Cells Improves Motor Function in Neurodegenerative Mice

Co-localization of Staufen1 with ATXN2 in stress-granule-like structures. ATXN2 and STAU1 co-localize in stress granules. Immunostaining of HEK-293 cells with antibodies against ATXN2, STAU1, and TIA-1 show co-localization of STAU1 with ATXN2 and TIA-1 in SGs during stress (0.5 mM sodium arsenite for 15 and 30 min) that are not present in the absence of stress. Scale bar, 10 µM. Credit: Paul et al 2018.



A Novel Epstein-Barr Virus-specific T Cell Therapy for Progressive MS


Mounting evidence shows that Epstein-Barr virus (EBV) plays a role in the pathology of multiple sclerosis. Consequently, an EBV-specific T Cell therapy has been developed to combat MS, and initial clinical trial results are promising.


Using Big Data to Reduce the Risk of Stroke


People with irregular and abnormally fast heart rates caused by a condition called atrial fibrillation could be at a greater risk of stroke and bleeding because they are not receiving optimal treatment, warn scientists from UCL and The University of Hong Kong (HKU).


Skype Helps Beat the Blues


Social isolation and depression have become commonplace in older adults, with estimates suggesting almost 5 percent of adults aged 50 and above lived with major depression in 2015. What if you could address the problem through communication technology?



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