An Emerging Revolution in Automated 3D Cell Culture
Poster Mar 13, 2007
Cal Trepagnier, Stacey Szymanski, Kevin Huff, Alision Rush, Richard Peltier, Berta strulovici, Rebecca Lobo and Robin Felder
Market pressure exists for new paradigms to meet the demands for more rapid and reproducible cell production to keep up with advances in cell-based assays used in drug discovery and development. Novel automation platforms enable high productivity on three dimensional surfaces.
Histone Deacetylase 6 (HDAC6) As A Therapeutic Target in Chronic Lymphocytic LeukemiaPoster
This study investigates the role of histone deacetylase 6 (HDAC6) in chronic lymphocytic leukemia and establishes it as a novel therapeutic target for the treatment of this disease.READ MORE
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and InvasionPoster
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
Comparison of CD45+ Depletion Methods for Enrichment of Disseminated Tumor Cells in Bone Marrow SamplesPoster
Comparison of CD45+ depletion methods for enrichment of disseminated tumor cells in bone marrow samples.READ MORE