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IntelliXtract 2.0: Simplified Intelligent Component Extraction and Detection

Poster   Mar 20, 2018

 
IntelliXtract 2.0: Simplified Intelligent Component Extraction and Detection
 
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Anne Marie Smith, Richard Lee, Vitaly Lashin, Andrey Paramonov

 
 

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

 
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Sport Doping Screening in Biological Matrices by Multi-Dimensional LC-QToF

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This work evaluated the performance of 2D LC variant using a QToF setup instead of a triple quadrupole mass spectrometer for the analysis of drug of abuse in urine targeting low and sub ppb level.

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Automation of Sample Preparation for Metabolomic Analysis Using Robotic Platform

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We developed an automated sample preparation protocol based on a robotic platform PAL RTC (CTC Analytics AG, Zwingen Switzerland), which represent a modified Bligh and Dyer method producing samples for both hydrophilic metabolomics using GC-MS and lipidomics using SFC-MS simultaneously.

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The Role of K13 in Artemisinin Resistance

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Plasmodium falciparum is evolving resistance to Artemisinin Combination Therapy. The gene with the strongest association with resistance is K13. K13 is an ortholog of the well characterized transcriptional regulator Keap1. In this work we transcriptionally characterized a mutant with a transposon inserted in the K13 promoter region which results in dysregulation of K13 at 2 points of the intraerythrocytic cycle of the life-cycle to identify the processes regulated by K13.

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Proteomics & Metabolomics

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